Clinical trial Recruiting at 1 site Observational Ages 18 and up

Investigating gut microbiota and genetics in inflammatory bowel diseases

Official title: Investigating the Intestinal Microbiota, Epigenetic Markers and Body Fluid Metabolites to Identify Biomarkers for Inflammatory Bowel Diseases

Run by Chinese University of Hong Kong · NCT03855657 · Data updated 2026-11-12

This study is trying to understand how gut bacteria and genetics affect inflammatory bowel diseases like ulcerative colitis and Crohn's disease, to help improve treatment for patients.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment6000 (estimated)
SponsorChinese University of Hong Kong
Academic / other
Locations1 site (Hong Kong)
StatusRecruiting
StartedMarch 2014
Main results expectedFebruary 2034
Study endsJuly 2034
Registry record updatedFebruary 8, 2023
Trial IDNCT03855657 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are adults aged 18 and older diagnosed with Crohn's disease or ulcerative colitis.

Probably not a fit

Patients with known current infections or those with a family history of IBD may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to establish a large-scale biobank to investigate the gut microbiota, genetics, epigenetics, and metabolites associated with inflammatory bowel diseases (IBD), specifically ulcerative colitis and Crohn's disease. It addresses the rising incidence of IBD in Asia and seeks to understand the interplay between genetic predisposition and environmental factors in disease development. By collecting comprehensive clinical data from patients, the study aims to personalize therapy and improve treatment outcomes for IBD patients.

Why it matters

Potential benefit: If successful, this study could lead to more personalized and effective treatment strategies for patients with inflammatory bowel diseases.

How similar studies have gone: Other studies have shown success in utilizing biobanks to investigate complex diseases, suggesting that this approach could yield valuable insights into IBD.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patient ≥18 with a diagnosis of Crohn's disease or ulcerative colitis
* Informed Consent obtained

Exclusion Criteria:

* Known current infection with an enteric pathogen
* Previously been diagnosed with IBD (Control)
* Have a first of second degree relative with IBD (Control)

Where it's running

  • Prince of Wales Hospital
    Hong Kong, Hong Kong
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.