Investigating gas distribution during mechanical ventilation in prostate surgery
Regional Distribution of Ventilation in Different Respiratory Rates: A Study of Mechanically Ventilated Patients Undergoing Robot-assisted Laparoscopic Prostatectomy
This study is testing if changing the breathing rate during mechanical ventilation can improve gas distribution and outcomes for patients having prostate surgery.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 15 (estimated) |
| Ages | 18 Years and up |
| Sex | Male |
| Sponsor | Region Örebro County Academic / other |
| Locations | 1 site (Örebro) |
| Trial ID | NCT06171477 on ClinicalTrials.gov |
What this trial studies
This study examines how gas is distributed in patients undergoing robot-assisted laparoscopic prostatectomy when subjected to different respiratory rates during mechanical ventilation. Using electric impedance tomography, the researchers will monitor ventilation distribution while adjusting the respiratory rate to determine if a higher frequency can lead to better outcomes and reduce the risk of ventilator-induced lung injuries. The study will include patients without known lung diseases and will collect data during standardized ventilation episodes at various respiratory rates.
Who should consider this trial
Good fit: Ideal candidates are adults over 18 scheduled for robot-assisted laparoscopic prostatectomy without prior lung disease.
Not a fit: Patients with known lung diseases or cognitive impairments may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved ventilation strategies that minimize lung injuries during surgery.
How similar studies have performed: While the approach of using electric impedance tomography for monitoring ventilation is established, the specific application in this context is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients planned for robot-assisted laparoscopic prostatectomy * \> 18 years * Consent to take part in the study Exclusion Criteria: * Impaired cognitive function * Previously known lung disease * Insufficient skills in Swedish language to understand information about the study
Where this trial is running
Örebro
- Region Örebro län — Örebro, Sweden (Recruiting)
Study contacts
- Study coordinator: Erik Wikström, MD
- Email: erik.wikstrom@regionorebrolan.se
- Phone: +46196025907
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.