Investigating Family History of Cancer in Non-Small Cell Lung Cancer Patients
Observational, Prospective, Multicentre Study to Investigate the Family History of Cancer in Patients With Non-small Cell Lung Cancer (FAHIC - Lung).
This study is looking to see if there's a link between family cancer history and non-small cell lung cancer in patients to help with genetic counseling.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 180 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Fondazione Policlinico Universitario Campus Bio-Medico Academic / other |
| Locations | 3 sites (Milan and 2 other locations) |
| Trial ID | NCT06196424 on ClinicalTrials.gov |
What this trial studies
This observational study aims to explore the family history of cancer in patients diagnosed with Non-Small Cell Lung Cancer (NSCLC). It will collect data through a self-reported questionnaire focusing on family cancer history, types of tumors, age at diagnosis, and smoking habits among relatives. The study seeks to identify patterns of familial cancer history and potential clusters of risk factors to guide genetic counseling for NSCLC patients. Participants will include individuals with histologically confirmed NSCLC, regardless of age or smoking status.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18 and older with a histopathological diagnosis of Non-Small Cell Lung Cancer.
Not a fit: Patients who do not have available family or personal cancer history data may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance understanding of inherited cancer risks and improve genetic counseling for patients with NSCLC.
How similar studies have performed: Previous studies have indicated a significant prevalence of genetic alterations linked to inherited cancer susceptibility in NSCLC, suggesting that this approach may yield valuable insights.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Histopathological diagnosis of Non-Small Cell Lung Cancer (all stages) * Age ≥ 18 years old * Signed informed consent * Availability of familiar and/or personal anamnestic data of cancer Exclusion Criteria: * Unavailability of familiar and/or personal anamnestic data of cancer * Patient's refusal
Where this trial is running
Milan and 2 other locations
- IRCCS Ospedale San Raffaele — Milan, Italy (Not_yet_recruiting)
- Fondazione Policlinico Universitario Campus Bio-Medico — Roma, Italy (Recruiting)
- AOU Citta della Salute le Molinette — Torino, Italy (Not_yet_recruiting)
Study contacts
- Study coordinator: Alessio Cortellini, MD PhD
- Email: a.cortellini@policlinicocampus.it
- Phone: 0039 06 22541 1
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.