Investigating extracellular vesicles in patients with Hairy Cell Leukemia

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to analyze extracellular vesicles (EV) in patients with Hairy Cell Leukemia (HCL) at various stages, including diagnosis, complete remission for over two years, and relapse requiring therapy. By examining the composition of these vesicles, the study seeks to uncover potential biomarkers related to the disease and its biology. The research will involve collecting plasma samples from patients and healthy donors to compare the EV signatures and understand their role in the tumor microenvironment.

Why it matters

Who can join: the full rules

Inclusion criteria for patients:

* WHO2022-defined diagnosis of Hairy Cell Leukemia.
* age ≥18 years.
* signed informed consent.

Inclusion criteria for Healthy Donors:

* age ≥18 years.
* Volunteers in general good health, free from any disease or serious illness.
* Signed informed consent.

Exclusion criteria

\- None

Where it's running

• IRCCS Azienda Ospedaliero-Universitaria di Bologna
  Bologna, Italy Recruiting

Study contacts

• Principal investigator: Lucia Catani, PhD — IRCCS Azienda Ospedaliero-Universitaria di Bologna
• Study coordinator: Lucia Catani, PhD
• Email: lucia.catani@unibo.it
• Phone: +390512143837

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.