Investigating epilepsy and its treatment options
Investigating Epilepsy: Screening and Evaluation
National Institutes of Health Clinical Center (CC) · NCT03478852
This study is looking to better understand epilepsy and improve treatments for people aged 8 and older who have drug-resistant epilepsy by examining their medical history and conducting tests.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 1000 (estimated) |
| Ages | 8 Years to 110 Years |
| Sex | All |
| Sponsor | National Institutes of Health Clinical Center (CC) (nih) |
| Locations | 1 site (Bethesda, Maryland) |
| Trial ID | NCT03478852 on ClinicalTrials.gov |
What this trial studies
This observational study aims to screen and evaluate individuals with diagnosed or suspected epilepsy to better understand the condition and improve treatment for those with drug-resistant epilepsy. Participants, aged 8 years and older, will undergo a series of evaluations including physical exams, medical history assessments, questionnaires, and various tests such as EEGs and MRIs. The collected clinical data will support ongoing NIH epilepsy-related research and help maintain a cohort for future studies. The study also seeks to follow the natural history of epilepsy and related disorders.
Who should consider this trial
Good fit: Ideal candidates include adults and children aged 8 years and older with a known or suspected diagnosis of epilepsy.
Not a fit: Patients with unstable medical conditions or those unable to travel to the NIH may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved treatment strategies for patients with drug-resistant epilepsy.
How similar studies have performed: Other studies have shown success in understanding epilepsy through similar observational approaches, indicating potential for valuable insights.
Eligibility criteria
Show full inclusion / exclusion criteria
* INCLUSION CRITERIA: * Age 8 years or older * Known or suspected diagnosis of epilepsy * Ability to give informed consent or have a legally authorized representative able to give consent (for adults without consent capacity) or parent/guardian able to provide informed consent (for a child) * If unable to give informed consent, ability to give assent (for minors 8 and older) EXCLUSION CRITERIA: * Patients with unstable medical conditions that, in the opinion of the investigators, makes participation unsafe, or who, in the opinion of the investigators may be unable to comply with the protocol * Patients who are unable to travel to the NIH
Where this trial is running
Bethesda, Maryland
- National Institutes of Health Clinical Center — Bethesda, Maryland, United States (RECRUITING)
Study contacts
- Principal investigator: Yasser Tajali, M.D. — National Institute of Neurological Disorders and Stroke (NINDS)
- Study coordinator: Aaliyah M HamidullahThiam
- Email: aaliyah.hamidullahthiam@nih.gov
- Phone: (301) 402-7686
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Seizures, Epilepsy, Epilepsy, Temporal Lobe, Partial Epilepsy, Seizure Disorder, Antiepileptic Drug, Natural History Study, Screening Protocol