Investigating elevated lipoprotein(a) levels in hospital staff
Investigating The Prevalence and Clinical Significance of Elevated Lipoprotein(a) Blood Levels in Hospital Staff
This study looks at how common high levels of lipoprotein(a) are among hospital staff and their families to see how it relates to heart health.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 2800 (estimated) |
| Ages | 21 Years to 100 Years |
| Sex | All |
| Sponsor | Changi General Hospital Academic / other |
| Locations | 1 site (Singapore) |
| Trial ID | NCT06304415 on ClinicalTrials.gov |
What this trial studies
This observational study aims to assess the prevalence of elevated lipoprotein(a) concentrations among healthcare workers and their family members. It will explore the distribution of lipoprotein(a) levels and their association with cardiovascular markers and outcomes. The study will involve a prospective approach, collecting data from participants aged 21 and above, as well as family members aged 12 and above, who meet specific inclusion criteria.
Who should consider this trial
Good fit: Ideal candidates for this study include healthcare workers aged 21 and above and their family members aged 12 and above with elevated lipoprotein(a) levels.
Not a fit: Patients who are pregnant, prisoners, or unable to provide informed consent will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance understanding of cardiovascular risk factors in healthcare workers and their families, potentially leading to improved screening and management strategies.
How similar studies have performed: While studies on lipoprotein(a) have been conducted, this specific focus on hospital staff and their families is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Any healthcare workers working in healthcare settings (regardless of PHI and/or private setting) aged 21 and above OR family member such as father, mother, siblings, grandparents, spouse and children aged 12 and above of recruited staff with high Lpa ≥120nmol/l 2. Study team members can also be recruited because we are trying to find the prevalence of elevated Lp(a) Exclusion Criteria: 1. Inability to provide informed consent. 2. Pregnant women. 3. Prisoner
Where this trial is running
Singapore
- Clinical Trials & Research Unit — Singapore, Singapore (Recruiting)
Study contacts
- Principal investigator: Loh Wann Jia — Singhealth Foundation
- Study coordinator: Clinical Trials & Research Unit
- Email: ctru@cgh.com.sg
- Phone: 64267818
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.