Clinical trial Recruiting at 2 sites Observational Ages 18 and up

Investigating circulating tumor cells in cancer patients

Official title: Circulating Tumor Cells (CTC) in Cancer

Run by University Hospital, Basel, Switzerland · NCT04520672 · Data updated 2026-11-12

This study is testing blood samples from adult cancer patients to see if circulating tumor cells can help us understand their cancer better and predict how they might do in the future.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment3000 (estimated)
SponsorUniversity Hospital, Basel, Switzerland
Academic / other
Locations2 sites (Basel and 1 other locations)
StatusRecruiting
StartedOctober 1, 2020
Main results expectedAugust 2030
Study endsAugust 2030
Registry record updatedMarch 12, 2025
Trial IDNCT04520672 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates include adult patients with a histologically confirmed diagnosis of solid tumors, such as adenocarcinoma or squamous cell carcinoma.

Probably not a fit

Patients with blood cancers or those who cannot provide written informed consent will not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study focuses on the collection and analysis of circulating tumor cells (CTCs) from blood samples of adult cancer patients at various stages of their disease. It aims to understand the biology of CTCs and their clusters, evaluating their potential as biomarkers for cancer progression and overall survival. The study will also explore key signaling networks active in CTCs across different cancer types, providing insights into their role in cancer biology.

Why it matters

Potential benefit: If successful, this study could enhance the understanding of cancer progression and improve patient monitoring through the use of CTCs as biomarkers.

How similar studies have gone: Other studies have shown promise in using circulating tumor cells as biomarkers, indicating that this approach has potential for success.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Adult cancer patients
* All patients with histology-based proved diagnosis of cancer, all stages and subtypes can be included. Precancerous lesions cannot be included.
* All patients with the diagnosis of a solid tumor including adenocarcinoma, squamous cell carcinoma, neuroendocrine carcinoma, sarcoma
* Written pathology report must be available.
* Written informed consent.

Exclusion Criteria:

* No written informed consent.
* No proved diagnosis of malignancy by pathology report.
* Patients with the diagnosis of blood cancer

Where it's running

  • University Hospital Basel
    Basel, Switzerland
    Recruiting
  • Department Oncology, Haematology & Immuntherapy, Kantonsspital Baselland
    Liestal, Switzerland
    Recruiting

Study contacts

  • Principal investigator: Marcus Vetter, PD Dr. med. — Kantonsspital Baselland, Liestal
  • Study coordinator: Marcus Vetter, PD Dr. med.
  • Email: marcus.vetter@ksbl.ch
  • Phone: +41 61 925 27 15

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.