Investigating chronic headaches after blood patch treatment in postpartum patients

Factors Associated With the Onset of Chronic Headaches in Patients Who Received a Blood Patch, Following an Accidental Dural Puncture During Post Partum Period

Assistance Publique - Hôpitaux de Paris · NCT05888324

This study is trying to find out what might cause chronic headaches in new mothers who had a blood patch treatment for headaches after childbirth.

Quick facts

Study typeObservational
Enrollment100 (estimated)
Ages18 Years and up
SexFemale
SponsorAssistance Publique - Hôpitaux de Paris (other)
Locations1 site (Paris, Ile De France)
Trial IDNCT05888324 on ClinicalTrials.gov

What this trial studies

This observational study aims to identify risk factors associated with the onset of chronic headaches in patients who received a blood patch to treat post-dural puncture headaches during the early postpartum period. Researchers will analyze various factors, including the conditions surrounding the accidental dural puncture, the initial symptoms of the headache, and the methods used for the blood patch procedure. Participants will be evaluated through phone questionnaires to assess the incidence of chronic headaches, low back pain, and any complications at 1 and 6 months post-treatment.

Who should consider this trial

Good fit: Ideal candidates are adults aged 18 and older who have undergone vaginal delivery or caesarean section with epidural anesthesia at the Port Royal maternity ward.

Not a fit: Patients who do not speak or understand French or those who had a blood patch performed for indications other than post-dural puncture headache may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could help identify risk factors that may prevent chronic headaches in postpartum patients after a blood patch procedure.

How similar studies have performed: While the association between blood patches and chronic headaches has been noted, this specific investigation into risk factors is novel and has not been extensively tested in previous studies.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age greater than or equal to 18 years old,
* Vaginal delivery or caesarean section with epidural at the Port Royal maternity ward,
* Collection of non-opposition after oral and written information,

Exclusion Criteria:

* Patient under curatorship or guardianship
* Not speaking/understanding French
* BP performed in another indication
* Benefiting from the AME (state medical aid)

Where this trial is running

Paris, Ile De France

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Blood Patch, Post-Dural Puncture Headache, Post Dural puncture headache, Epidural blood patch, Chronic headache, Epidural analgesia, Obstetric anaesthesia

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.