Investigating Campylobacter Infections in Bone and Joint Conditions
Campylobacter Spp. Bone and Joint Infection: a Retrospective Cohort Study
Hospices Civils de Lyon · NCT06425250
This study looks at how Campylobacter infections affect people with bone and joint problems to see what makes these infections last and how well treatments work.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 200 (estimated) |
| Ages | 18 Years to 100 Years |
| Sex | All |
| Sponsor | Hospices Civils de Lyon (other) |
| Locations | 1 site (Lyon) |
| Trial ID | NCT06425250 on ClinicalTrials.gov |
What this trial studies
This observational study examines the management and risk factors associated with bone and joint infections caused by Campylobacter species. It focuses on patients diagnosed with various types of osteoarticular infections between 2013 and 2022, analyzing clinical signs, diagnostic methods, and treatment outcomes. The study aims to gather data on the persistence of these infections and the challenges posed by antibiotic resistance, contributing to a better understanding of Campylobacter's role in osteoarticular infections.
Who should consider this trial
Good fit: Ideal candidates include adults over 18 with a confirmed diagnosis of osteoarticular infection involving Campylobacter spp.
Not a fit: Patients without a diagnosis of osteoarticular infection or those under 18 years old may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could improve the management and treatment strategies for patients suffering from Campylobacter-related bone and joint infections.
How similar studies have performed: While there is limited research specifically on Campylobacter in osteoarticular infections, the study builds on existing knowledge of Campylobacter infections in other contexts, suggesting potential for valuable insights.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * \> 18 years * Osteoarticular infection (whatever its type), mono or polymicrobial with Campylobacter spp., diagnosed between 01/01/2013 and 12/31/2022: * Septic arthritis: compatible clinical signs + joint fluid sample positive in culture and/or PCR positive for Campylobacter * Spondylodiscitis: clinical signs and MRI compatible + blood cultures and/or disco-vertebral biopsy puncture positive in culture and/or PCR positive for Campylobacter * Osteitis/osteomyelitis: compatible clinico-radiological picture + bone sample (biopsy or intraoperative sample) positive in culture and/or positive PCR for Campylobacter * Infection on joint prosthesis or osteosynthesis equipment: documented Campylobacter infection and meeting the definition of probable or confirmed JIBS infections * Patient who was informed and did not object to participating in the study Exclusion Criteria: \-
Where this trial is running
Lyon
- Service des maladies infectieuses et tropicales - Hôpital de la Croix-Rousse — Lyon, France (RECRUITING)
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Campylobacter Infections, Management, Risk factors, Campylobacter spp.