Intraoperative MRI to improve brain metastasis surgery
Evaluation of the Efficacy and Safety of Intraoperative MRI in the Surgery of Brain Metastases.
NA · Technical University of Munich · NCT07197632
This study will test whether using intraoperative MRI during surgery helps surgeons remove brain metastases more completely and with fewer repeat operations.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 154 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Technical University of Munich (other) |
| Locations | 1 site (Munich) |
| Trial ID | NCT07197632 on ClinicalTrials.gov |
What this trial studies
Adults who require surgical resection of brain metastases will receive neurosurgical removal guided by intraoperative 3T MRI to improve tumor visualization during the operation. Outcomes tracked will include extent of resection, need for additional procedures, operative time, and complication rates. The trial excludes patients with contraindications to 3T MRI and those under 18 years of age. The work is carried out at the Department of Neurosurgery, Munich University Hospital (rechts der Isar) under the Technical University of Munich.
Who should consider this trial
Good fit: Adults (18+) with brain metastases for which surgical resection is indicated and who can safely undergo 3T MRI are the best candidates.
Not a fit: Patients who cannot have 3T MRI, are not surgical candidates, or whose metastases are unsuitable for resection are unlikely to benefit from this approach.
Why it matters
Potential benefit: If successful, this approach could enable more complete tumor removal in the first operation, potentially reducing repeat surgeries and improving recovery.
How similar studies have performed: Intraoperative MRI has improved resection rates in glioma surgery, but evidence specifically for brain metastases is limited and mixed.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients for whom surgical resection of brain metastasis is indicated Exclusion Criteria: * age \< 18 * 3T MRI contraindications
Where this trial is running
Munich
- Department of Neurosurgery, München University Hospital rechts der Isar (MRI) — Munich, Germany (RECRUITING)
Study contacts
- Study coordinator: Maria Goldberg
- Email: maria.goldberg@tum.de
- Phone: +498941402151
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Brain Metastases, ioMRI, Brain metastases, Neurosurgical resection