Clinical trial Recruiting at 1 site Interventional Ages 18 and up

Intraoperative MRI to improve brain metastasis surgery

Official title: Evaluation of the Efficacy and Safety of Intraoperative MRI in the Surgery of Brain Metastases.

Run by Technical University of Munich · NCT07197632 · Data updated 2026-11-12

This study will test whether using intraoperative MRI during surgery helps surgeons remove brain metastases more completely and with fewer repeat operations.

Quick facts

Study typeInterventional
Ages18 Years and up
SexAll
Enrollment154 (estimated)
SponsorTechnical University of Munich
Academic / other
Locations1 site (Munich)
StatusRecruiting
StartedJanuary 17, 2025
Main results expectedJanuary 1, 2027
Study endsJanuary 1, 2030
Registry record updatedMay 5, 2026
Trial IDNCT07197632 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults (18+) with brain metastases for which surgical resection is indicated and who can safely undergo 3T MRI are the best candidates.

Probably not a fit

Patients who cannot have 3T MRI, are not surgical candidates, or whose metastases are unsuitable for resection are unlikely to benefit from this approach.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Adults who require surgical resection of brain metastases will receive neurosurgical removal guided by intraoperative 3T MRI to improve tumor visualization during the operation. Outcomes tracked will include extent of resection, need for additional procedures, operative time, and complication rates. The trial excludes patients with contraindications to 3T MRI and those under 18 years of age. The work is carried out at the Department of Neurosurgery, Munich University Hospital (rechts der Isar) under the Technical University of Munich.

Why it matters

Potential benefit: If successful, this approach could enable more complete tumor removal in the first operation, potentially reducing repeat surgeries and improving recovery.

How similar studies have gone: Intraoperative MRI has improved resection rates in glioma surgery, but evidence specifically for brain metastases is limited and mixed.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients for whom surgical resection of brain metastasis is indicated

Exclusion Criteria:

* age \< 18
* 3T MRI contraindications

Where it's running

  • Department of Neurosurgery, München University Hospital rechts der Isar (MRI)
    Munich, Germany
    Recruiting

Study contacts

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.