Intervention for adolescents and young adults with cancer to improve social health

The Promoting Resilience in Stress Management-Social Needs (PRISM-SN) Intervention for Adolescents and Young Adults With Cancer: A Randomized Controlled Trial

Not applicable Interventional Seattle Children's Hospital · NCT06242964

This study is testing a new program to help young people recently diagnosed with cancer improve their social skills and overall well-being compared to regular support.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment100 (estimated)
Ages12 Years to 25 Years
SexAll
SponsorSeattle Children's Hospital Academic / other
Drugs / interventionschemotherapy, radiation
Locations1 site (Seattle, Washington)
Trial IDNCT06242964 on ClinicalTrials.gov

What this trial studies

This study aims to evaluate the feasibility and acceptability of the Promoting Resilience in Stress Management - Social Needs (PRISM-SN) intervention for adolescents and young adults (AYAs) newly diagnosed with cancer. Participants will be randomly assigned to receive either usual psychosocial care or the PRISM-SN program, which includes skill-based behavioral modules designed to enhance social functioning. The effectiveness of the intervention will be assessed through patient-reported outcome surveys at enrollment and after 12 weeks. The study seeks to determine if the PRISM-SN program leads to improved psychosocial outcomes compared to standard care.

Who should consider this trial

Good fit: Ideal candidates are adolescents and young adults aged 12-25 who have been newly diagnosed with cancer and are undergoing chemotherapy and/or radiation.

Not a fit: Patients with recurrent malignancies or those who are not currently receiving chemotherapy or radiation may not benefit from this study.

Why it matters

Potential benefit: If successful, this intervention could significantly enhance the social and psychological well-being of young cancer patients.

How similar studies have performed: Other studies have shown promise in psychosocial interventions for cancer patients, suggesting that this approach could be beneficial.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Aged 12-25 years
* Diagnosed with new malignancy treated with chemotherapy and/or radiation \<6-months
* Able to speak in the English language
* Able to read in the English language
* Cognitively able to participate in intervention sessions and complete surveys

Exclusion Criteria:

* Aged \<12 or \>25 years
* Diagnosed with recurrent malignancy
* Diagnosed with new malignancy \>6 months
* Not receiving chemotherapy and/or radiation
* Not able to speak in the English language
* Not able to read in the English language
* Not cognitively able to participate in intervention session or complete surveys

Where this trial is running

Seattle, Washington

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions CancerSocial FunctioningPsychosocial FunctioningCoping Skills
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.