Clinical trial Recruiting at 1 site Interventional Ages 15 to 18

Interpersonal Psychotherapy for adolescents with depression

Official title: Interpersonal Psychotherapy for Adolescents and Young Adults

Run by Linnaeus University · NCT05575960 · Data updated 2026-11-12

This study is testing if Interpersonal Psychotherapy can help teenagers with major depression feel better by improving their emotions and social connections.

Quick facts

Study typeInterventional
Ages15 Years to 18 Years
SexAll
Enrollment60 (estimated)
SponsorLinnaeus University
Academic / other
Locations1 site (Norrköping)
StatusRecruiting
StartedOctober 3, 2022
Main results expectedDecember 31, 2026
Study endsJune 15, 2027
Registry record updatedMay 20, 2024
Trial IDNCT05575960 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are adolescents aged 15 to 17.5 years diagnosed with major depressive disorder.

Probably not a fit

Patients with ongoing psychosis, severe depression requiring hospitalization, or those with substance abuse issues may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This project aims to evaluate the effectiveness of Interpersonal Psychotherapy (IPT) specifically for adolescents suffering from major depression. Over four years, the study will recruit 60 patients and utilize a quasi-experimental multiple-baseline design to assess treatment outcomes. Key aspects being analyzed include change mechanisms such as mentalizing, emotion regulation, and social support, along with predictors of treatment effectiveness. The implementation of IPT will also be examined through qualitative interviews with participants and their families.

Why it matters

Potential benefit: If successful, this study could provide an effective therapeutic approach for adolescents dealing with major depression.

How similar studies have gone: Previous studies have shown positive outcomes for IPT in treating depression, suggesting that this approach may be effective for adolescents as well.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Major depressive disorder according to the DSM-V
* Age 15 to 17,5 years.
* Good-enough knowledge in Swedish to be able to read instructions in questionnaires and who do not require an interpreter.

Exclusion Criteria:

* Ongoing psychosis
* Drug or alcohol addiction
* Bipolar disorder
* Suspected mental retardation
* Acute suicidality or severe depression requiring hospitalization
* Patients who have started antidepressant medication within the last six weeks will need to wait until medication effects have stabilized.

Where it's running

  • Norrköping Child and Adolescent Psychiatric Services (BUP Norrköping)
    Norrköping, Sweden
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.