Clinical trial No longer in our active list Interventional Ages 18 and up

Intermittent fasting for improving psoriasis and psoriatic arthritis

Official title: Role of Intermittent Fasting on Disease Severity and Quality of Life in Psoriasis and Psoriatic Arthritis

Run by Ohio State University · NCT05590247 · Data updated 2026-05-14

This study is no longer in our active list. It may have stopped recruiting or finished. The details below are as of 2026-05-14 and are kept for reference. Check ClinicalTrials.gov for its current status, or see similar studies below.

This study tests if intermittent fasting can help improve symptoms for people with psoriasis and psoriatic arthritis.

Quick facts

Study typeInterventional
Ages18 Years and up
SexAll
Enrollment60 (estimated)
SponsorOhio State University
Academic / other
Locations1 site (Columbus, Ohio)
Trial IDNCT05590247 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults aged 18 and older with mild to moderate plaque psoriasis who are overweight and have not changed their systemic treatment for at least six weeks.

Probably not a fit

Patients who are pregnant, breastfeeding, insulin-dependent diabetics, or have severe comorbid conditions may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the effects of intermittent fasting on the severity of psoriasis and psoriatic arthritis in patients at Ohio State University. Participants will be randomly assigned to either an intermittent fasting group or a standard diet group for 24 weeks. The study will assess changes in disease severity and quality of life through clinical evaluations and patient-reported outcomes. Follow-up assessments will occur every four weeks, with a focus on the feasibility of a larger study based on the results.

Why it matters

Potential benefit: If successful, this approach could provide a novel dietary intervention to improve symptoms and quality of life for patients with psoriasis and psoriatic arthritis.

How similar studies have gone: While intermittent fasting has been explored in various contexts, this specific application for psoriasis and psoriatic arthritis is novel and has not been extensively tested.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* 18 years of age and older
* Established patient at the clinical site with a diagnosis of mild to moderate plaque psoriasis despite treatment
* Ability to consent and follow dietary instructions
* Overweight (BMI ≥ 25)
* No change in systemic psoriasis treatment for 6 weeks

Exclusion Criteria:

* Pregnancy and/or breastfeeding
* Insulin-dependent diabetics
* Severe heart, kidney, and liver disease
* Obesity due to medical condition
* Use of medical treatment for weight reduction

Where it's running

  • The Ohio State University Wexner Medical Center
    Columbus, Ohio, United States
    Recruiting

Study contacts

  • Principal investigator: Benjamin H Kaffenberger, MD, MS — Ohio State University
  • Study coordinator: Ashley N Gray, BS
  • Email: ashley.gray@osumc.edu
  • Phone: 6142931707

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.