Clinical trial Recruiting at 1 site Interventional Ages 55 Months to 85 Months

Integrated vs. Sequential Dual-Task Training for older adults with mild to moderate cognitive impairment

Official title: Comparative Effects of Integrated Versus Sequential Approaches to Dual-Task Training in Elderly With Mild to Moderate Cognitive Impairment: A Four-Arm Randomized Controlled Trial

Run by Shifa Tameer-e-Millat University · NCT07775079 · Data updated 2026-11-12

This study tests whether combining cognitive and physical tasks at the same time is more helpful than doing them separately for people over 55 with mild to moderate cognitive impairment.

Quick facts

Study typeInterventional
Ages55 Months to 85 Months
SexAll
Enrollment96 (estimated)
SponsorShifa Tameer-e-Millat University
Academic / other
Locations1 site (Islamabad, Islamabad)
StatusRecruiting
StartedJune 25, 2026
Main results expectedAugust 25, 2026
Study endsAugust 30, 2026
Registry record updatedAugust 21, 2026
Trial IDNCT07775079 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults over 55 with MoCA scores 10–25 and MMSE scores 10–23, diagnosed with cognitive impairment, and able to participate in training.

Probably not a fit

Individuals with severe cognitive impairment, severe physical or sensory limitations, unstable medical conditions, or participation in other trials may not benefit.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The trial compares integrated dual-task training with sequential dual-task training in older adults who have mild to moderate cognitive impairment. Participants are randomly assigned to either the integrated approach or the sequential approach, with outcome measures focused on cognitive function and physical performance. The program targets everyday tasks like walking while counting or other cognitive challenges to promote neuroplasticity. The study is conducted at PIMS Hospital Islamabad, led by Shifa Tameer-e-Millat University. Eligibility includes age over 55 and specific MoCA and MMSE ranges.

Why it matters

Potential benefit: If successful, the approach could improve cognitive and physical functioning and quality of life for older adults with cognitive impairment.

How similar studies have gone: Prior research supports dual-task training in rehabilitation, though direct comparisons between integrated and sequential approaches are less established.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age \> 55 years
* MoCA: 10-25
* MMSE: 10-23
* Diagnosed cognitive impairment
* Able to participate in training

Exclusion Criteria:

* Severe cognitive impairment
* Severe physical sensory limitations
* Unstable medical conditions
* Participation in other trials

Where it's running

  • PIMS Hospital Islamabad
    Islamabad, Islamabad, Pakistan
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

  • Oral Motor and Cognitive Dual-Task Training for Oral Frailty and Cognitive Impairment

    This program tests if combining oral-motor exercises with simple thinking tasks can improve mouth function and thinking skills in adults with oral frailty and mild-to-moderate cognitive impairment.

    Recruiting The Hong Kong Polytechnic University · Kowloon, Hong Kong and 1 other locations · NCT07733726

  • Rural Veterans and Care Partners Walking Program

    A virtual walking program is tested to see if it can help Veterans with mild cognitive impairment and their care partners in rural areas walk more each day.

    Recruiting Creighton University · Omaha, Nebraska · NCT07914218

  • China HEAD: a large community study on healthy aging and dementia

    This study tests whether collecting health, imaging, and biospecimen data from adults in China can help predict who will develop Alzheimer’s disease and related dementias.

    Recruiting at 30 sites Fudan University · Beijing and 29 other locations · NCT07912710

  • Aging Brain Health Initiative in Fujian

    This observational study will follow about 3,000 older adults in Fujian to see how Alzheimer's-related changes develop and to test new digital tests, biomarkers, and imaging tools for early diagnosis.

    Recruiting at 4 sites Fujian Medical University Union Hospital · Fushun, Fujian and 3 other locations · NCT07891429

  • See if multimodal biomarkers can map changes from mild cognitive impairment to dementia

    This observational study tests whether clinical, blood, and brain-imaging markers can tell apart stages of cognitive decline and predict progression from mild cognitive impairment to dementia in about 600 people.

    Recruiting Xuanwu Hospital, Beijing · Beijing, Beijing Municipality · NCT07876570

  • LIFU to Help Sleep and Amyloid Reduction in Older Adults with Cognitive Impairment

    A wearable ultrasound device (ATTN201) is being tested to see if it’s safe and easy to use for people 65 and older with mild cognitive impairment and amyloid buildup.

    Recruiting University of California, San Francisco · San Francisco, California · NCT07866768

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.