Integrated recovery program for ICU survivors

Integrated Critical Illness Aftercare and Recovery Enhancement (I-CARE) Program

NA · National Taiwan University Hospital · NCT06997822

This trial will test whether combining a LINE Bot remote support system with in-person post-ICU clinic visits can reduce unplanned readmissions and improve physical and cognitive recovery for people who were intubated in the ICU.

Quick facts

PhaseNA
Study typeInterventional
Enrollment240 (estimated)
Ages18 Years and up
SexAll
SponsorNational Taiwan University Hospital (other)
Locations1 site (Taipei)
Trial IDNCT06997822 on ClinicalTrials.gov

What this trial studies

This randomized trial compares an integrated aftercare program (LINE Bot remote monitoring plus scheduled in-person post-ICU recovery clinic visits) to usual follow-up for ICU survivors who received mechanical ventilation. The primary outcome is the rate of unplanned hospital readmissions and emergency department visits within six months after discharge. Secondary outcomes include physical mobility measures, inspiratory muscle strength, weight change, dysphagia, and cognitive function assessed at 3 and 6 months. The LINE Bot also includes a 'Thanks to Nurses' feature, and the study will measure ICU nurses' burnout and intention to leave at 6, 12, 18, and 24 months.

Who should consider this trial

Good fit: Ideal participants are ICU survivors who were intubated and mechanically ventilated, can walk independently prior to admission, can use a smartphone (LINE), and are being discharged home rather than to an institutional facility.

Not a fit: Patients discharged to institutional care, those with significant preexisting dementia or inability to participate in assessments, or those without a smartphone are unlikely to benefit from this program.

Why it matters

Potential benefit: If successful, the program could lower emergency visits and readmissions while improving mobility, breathing strength, weight recovery, and thinking skills after ICU stay.

How similar studies have performed: Previous work on post-ICU clinics and remote follow-up has shown mixed but promising results for reducing readmissions and improving function, and this study builds on that evidence while adding a novel nurse–patient communication feature.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* ICU survivors who had experienced endotracheal intubation and mechanical ventilation treatment.

Exclusion Criteria:

* ICU survivors who are unable to walk independently before admission
* ICU survivors who are unable to receive assessment (e.g., dementia or mental retardation)
* ICU survivors who don't have a smartphone.
* ICU survivors were discharged to institutional care facilities

Where this trial is running

Taipei

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: ICU Survivors, ICU survivors, Physical function, Cognitive, Weight loss

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.