Inspiratory muscle training for people with substance use disorder
The Effect of Inspiratory Muscle Training With Substance Use Disorder
This project will try inspiratory muscle training to see if it helps adults with substance use disorder breathe better, improve exercise capacity, and reduce cravings.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 34 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Uskudar University Academic / other |
| Locations | 1 site (Istanbul, Turkey) |
| Trial ID | NCT06961838 on ClinicalTrials.gov |
What this trial studies
Adults receiving inpatient treatment for substance use disorder at Üsküdar University will be assigned to an inspiratory muscle training program or a control group and followed for respiratory and clinical outcomes. The program uses targeted inspiratory muscle exercises to strengthen breathing muscles and is compared with usual care. Measured outcomes include dyspnea, pulmonary function, respiratory muscle strength, cough capacity, functional exercise capacity, substance craving, depression, anxiety, and quality of life. The investigators note this is the first study specifically testing inspiratory muscle training in people with substance use disorders.
Who should consider this trial
Good fit: Adults (over 18) with DSM-5 substance use disorder who are receiving inpatient treatment, have used substances for more than one year, can follow simple instructions, and have no active respiratory infections or major physical/psychotic problems are ideal candidates.
Not a fit: People with active respiratory diseases (like asthma or tuberculosis), infectious conditions (e.g., HIV, hepatitis B), current psychosis, significant physical disabilities, recent participation in structured physiotherapy, or those not in inpatient treatment are unlikely to benefit from this program as studied.
Why it matters
Potential benefit: If successful, this could provide a simple, low-cost therapy to improve breathing, exercise capacity, mood, and reduce cravings in people with substance use disorder.
How similar studies have performed: Inspiratory muscle training has shown benefits for breathing and exercise capacity in other respiratory and rehabilitation populations, but to our knowledge it has not been previously tested specifically in people with substance use disorder.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Being older than 18 years * Meeting the current Diagnostic and Statistical Manual of Mental Disorders, 5th edition (DSM-5) criteria for Substance Use Disorder * Receiving inpatient treatment * Substance use for more than one year * Being able to follow simple instructions * Not having any visual and auditory pathology * Being able to cooperate with the devices used. Exclusion Criteria: * Failure to comply with the treatment and assessment program * Participation in a structured physiotherapy/exercise program in the last 6 months * Presence of current psychotic symptoms * Presence of any physical disability or medical problem * Presence of respiratory system problems such as asthma and tuberculosis and infectious health problems (e.g. HIV, hepatitis B).
Where this trial is running
Istanbul, Turkey
- Üsküdar University — Istanbul, Turkey, Turkey (Türkiye) (Recruiting)
Study contacts
- Study coordinator: Beyzanur D Research Assistant
- Email: beyzanur.dikmenhosbas@uskudar.edu.tr
- Phone: + (0216) 400 22 22
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.