Inspiratory muscle training for adults with asthma: effects on activity, coping, and self-management
Reflections of Inspiratory Muscle Training on Patient Experiences in Asthma Rehabilitation
This project will try an 8-week inspiratory muscle training program delivered by videoconference plus home sessions to see if it changes activity levels, coping skills, and self-management in adults with severe non-allergic asthma.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 15 (estimated) |
| Ages | 18 Years to 65 Years |
| Sex | All |
| Sponsor | Istanbul Esenyurt University Academic / other |
| Locations | 1 site (Istanbul, Istanbul) |
| Trial ID | NCT07320066 on ClinicalTrials.gov |
What this trial studies
Researchers will use a qualitative design to capture patient experiences after an 8-week inspiratory muscle training (IMT) program delivered twice weekly via videoconference plus a home session each week. Participants who completed the IMT protocol (seven 2-minute work sets with 1-minute rests, three times per week) and pulmonary rehabilitation will be interviewed about how the program affected daily activities, symptom coping, and self-care. Interviews will be analyzed thematically to identify major themes such as IMT experiences, telerehabilitation factors, changes in physical activity, self-management skills, and coping strategies. Findings aim to clarify patient-perceived effects and barriers to using IMT delivered by telerehab.
Who should consider this trial
Good fit: Adults aged 18–65 with a pulmonologist-confirmed diagnosis of severe persistent non-allergic asthma, documented type 2 inflammation markers within study criteria, bronchodilator responsiveness, who have completed pulmonary rehabilitation and an 8-week IMT program are ideal candidates.
Not a fit: Patients with recent respiratory infection, a smoking history over 10 pack-years, allergic asthma profiles, or who have not completed the required 8-week IMT program are unlikely to match the study profile or gain relevant findings.
Why it matters
Potential benefit: If successful, the findings could help tailor IMT and telehealth delivery to better support physical activity, coping, and self-management for adults with severe non-allergic asthma.
How similar studies have performed: Inspiratory muscle training has shown symptomatic and strength benefits in other respiratory populations (notably COPD) and some asthma work, but qualitative evidence on patient experience with IMT delivered via telerehabilitation is limited and relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Being between the ages of 18-65 * Having been diagnosed with severe persistent, non-allergic asthma by a pulmonologist in accordance with the Global Initiative for Asthma (GINA) guideline criteria, * Patients with type 2 inflammation markers. According to accepted standards; peripheral eosinophils \<150/µL and/or negative skin prick test and/or total IgE \<30 kU/L * Bronchodilator response (\>12% or 200 mL improvement in FEV1% predicted following inhalation of 400 mg salbutamol) * Diagnosis-follow-up period: Patients diagnosed at least 6 months prior, under follow-up and treatment, and/or with controlled asthma * Having completed the pulmonary rehabilitation program * Completion of 8 weeks of inspiratory muscle training (IMT) * Patients who have read, understood, and signed the informed consent form Exclusion Criteria: * Having recently had a respiratory tract infection recently (within the last month), * Having a smoking history of more than 10 pack-years or having a history of smoking within 6 months after quitting smoking * Having received oral corticosteroid treatment in the last 4 weeks, * Having a Body Mass Index \>35, * Eosinophilic Granulomatosis Polyangiitis (EGPA) and Allergic Bronchopulmonary Aspergillosis (ABPA), * Vasculitis, * History of malignancy, * Pregnancy, * Previous lung surgery, use of long-term oxygen therapy * Having accompanying restrictive lung diseases (advanced kyphoscoliosis, ankylosing spondylitis) and neuromuscular diseases (myastania gravis, muscular dystrophies, myopathies) that will prevent healthy respiratory function testing and rehabilitation. * Cognitive dysfunction, mental retardation, dementia, or other conditions that make it difficult to follow the protocol, * Unwillingness to continue participating in the study, * Communication difficulties or intellectual deficiencies
Where this trial is running
Istanbul, Istanbul
- Istanbul Esenyurt University — Istanbul, Istanbul, Turkey (Türkiye) (Recruiting)
Study contacts
- Study coordinator: Esra PEHLİVAN, PhD
- Email: fztesrakambur@yahoo.com
- Phone: +90 216 777 96 00
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.