Injection therapy using dextrose for knee arthritis
The Effects and Molecular Mechanisms of Dextrose Prolotherapy on Articular Cartilage
NA · Chang Gung Memorial Hospital · NCT06301958
This study is testing whether dextrose injections can help people with knee arthritis feel better and improve their healing.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 60 (estimated) |
| Ages | 20 Years and up |
| Sex | All |
| Sponsor | Chang Gung Memorial Hospital (other) |
| Locations | 1 site (Chiayi City, 嘉義市) |
| Trial ID | NCT06301958 on ClinicalTrials.gov |
What this trial studies
This clinical trial investigates the effects of dextrose prolotherapy, a controversial injection therapy, on patients suffering from knee arthritis. The study aims to explore the molecular mechanisms behind the therapeutic effects of a 25% hypertonic glucose solution, which is commonly used in clinical practice. By examining how this treatment influences local inflammation and healing processes, the researchers hope to optimize its application for better patient outcomes. The trial will involve adult participants who meet specific eligibility criteria and will assess the efficacy of this treatment approach.
Who should consider this trial
Good fit: Ideal candidates for this study are adult men and women diagnosed with knee arthritis who are willing to participate.
Not a fit: Patients who are pregnant, lactating, have septic arthritis, or have undergone joint surgery within the last 30 days may not benefit from this study.
Why it matters
Potential benefit: If successful, this treatment could provide a novel and effective option for managing knee arthritis pain.
How similar studies have performed: While dextrose prolotherapy has been used in clinical practice, the specific mechanisms and efficacy of this approach are still under investigation, making this study a valuable exploration in a somewhat controversial area.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Willing to sign a written consent form * Adult men and women with arthritis Exclusion Criteria: * Pregnant or lactating women * Septic arthritis * Those who have undergone joint surgery within 30 days
Where this trial is running
Chiayi City, 嘉義市
- Chang Gung Memorial Hospital, Chiayi — Chiayi City, 嘉義市, Taiwan (RECRUITING)
Study contacts
- Principal investigator: Hung-Chih Hsu, PhD — Chang Gung Memorial Hospital, Chiayi
- Study coordinator: Hung-Chih Hsu, PhD
- Email: dr.tonyhsu@gmail.com
- Phone: +886-3-3621000
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Arthritis Knee, Dextrose, Prolotherapy, Joint Pain, Synovial Fluid