Injection of Bupivacaine and Epinephrine for Sinus Surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial investigates the effects of injecting a combination of bupivacaine and epinephrine during endoscopic sinus surgery (ESS) to determine if it improves surgical visualization compared to a sham injection. The study aims to assess whether this intervention can reduce bleeding and enhance the surgeon's ability to perform the procedure effectively. Participants will be adults scheduled for primary ESS, and the outcomes will be compared between those receiving the active injection and those receiving a placebo.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age 19 years or older
* Scheduled for primary ESS (including septoplasty)

Exclusion Criteria:

* Cystic fibrosis
* Systemic vasculitis or any bleeding disorders
* Known or suspected hypersensitivity to bupivacaine or epinephrine
* Previous sinus surgery
* Inhaled drug use (i.e., cocaine) in the preceding 6 months
* Nasal tumors
* Patients on antiarrhythmics.
* Patients with history of severe liver illness.
* Patients identified as high-risk for complications during preoperative assessment with the anesthesiologist (e.g. untreated hypertension, ischemic heart disease, cerebral vascular insufficiency, heart block, peripheral vascular disorder, uncontrolled hyperthyroidism and diabetes)

Where it's running

• St.Paul's Hospital Sinus Center
  Vancouver, British Columbia, Canada Recruiting

Study contacts

• Study coordinator: Amin Javer
• Email: sinusdoc@me.com
• Phone: 6048069926

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.