Increasing PrEP uptake among Latino men who have sex with men in Puerto Rico

Optimizing PrEP Uptake Among Latino MSM in Puerto Rico: A Comparative Effectiveness Study

Not applicable Interventional University of Puerto Rico · NCT05804461

This study is trying out a new way to encourage Latino men who have sex with men in Puerto Rico to use PrEP, a medication that helps prevent HIV, by addressing their concerns and barriers to access.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment182 (estimated)
Ages21 Years to 99 Years
SexMale
SponsorUniversity of Puerto Rico Academic / other
Locations1 site (San Juan)
Trial IDNCT05804461 on ClinicalTrials.gov

What this trial studies

This study aims to develop and evaluate a Motivational Interviewing Intervention designed to enhance the uptake of Pre-Exposure Prophylaxis (PrEP) among Latino men who have sex with men (MSM) in Puerto Rico. The intervention will focus on addressing barriers to PrEP access and adherence, utilizing motivational interviewing techniques to engage participants effectively. Eligible participants include HIV-negative or unknown status Latino MSM aged 21 and older who meet specific criteria for PrEP use. The study will be conducted at the University of Puerto Rico Medical Sciences Campus.

Who should consider this trial

Good fit: Ideal candidates for this study are Latino MSM aged 21 and older who are HIV-negative or have an unknown status and meet CDC criteria for PrEP eligibility.

Not a fit: Patients who are HIV positive or unable to read and write in Spanish will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could significantly increase PrEP uptake among Latino MSM, thereby reducing the risk of HIV transmission in this population.

How similar studies have performed: Other studies have shown success in using motivational interviewing to improve health outcomes, suggesting this approach may be effective in increasing PrEP uptake.

Eligibility criteria

Show full inclusion / exclusion criteria
Latino MSM group - Inclusion Criteria:

* Biological male
* Age 21 or older
* Self-reported HIV negative or unknown status
* Not using PrEP (participants who have discontinued PrEP use can participate in the study), Spanish fluency (ability to write and read in Spanish)
* Presenting at least one of the eligibility criteria for PrEP as established by the CDC (including men who have had an infection (STI) in the past 6 months, HIV positive sexual partner)
* Access to a portable technology device (e.g., phone, tablet, laptop) or desktop computer access to internet connection

Exclusion Criteria:

* HIV positive individual
* Evidence of being under the effects of alcohol or drugs
* Indication of unstable or serious psychiatric symptoms
* Evidence of major cognitive impairment
* Inability to speak and read in Spanish

Healthcare Providers group - Inclusion Criteria:

* Age 21 or older
* Providing PrEP related health services at time of enrollment (e.g., case management, clinical services)
* Spanish fluency (ability to write and read in Spanish)

Exclusion Criteria:

* Evidence of being under the effects of alcohol or drugs
* Indication of unstable or serious psychiatric symptoms
* Evidence of major cognitive impairment
* Inability to speak and read in Spanish

Where this trial is running

San Juan

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions HIV Prevention
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.