Clinical trial Recruiting at 1 site Interventional Ages 21 to 99 Men only

Increasing PrEP uptake among Latino men who have sex with men in Puerto Rico

Official title: Optimizing PrEP Uptake Among Latino MSM in Puerto Rico: A Comparative Effectiveness Study

Run by University of Puerto Rico · NCT05804461 · Data updated 2026-11-12

This study is trying out a new way to encourage Latino men who have sex with men in Puerto Rico to use PrEP, a medication that helps prevent HIV, by addressing their concerns and barriers to access.

More HIV Prevention trials

Quick facts

Study typeInterventional
Ages21 Years to 99 Years
SexMen only
Enrollment182 (estimated)
SponsorUniversity of Puerto Rico
Academic / other
Locations1 site (San Juan)
StatusRecruiting
StartedSeptember 1, 2023
Main results expectedMay 31, 2027
Study endsMay 31, 2027
Registry record updatedJuly 15, 2026
Trial IDNCT05804461 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are Latino MSM aged 21 and older who are HIV-negative or have an unknown status and meet CDC criteria for PrEP eligibility.

Probably not a fit

Patients who are HIV positive or unable to read and write in Spanish will not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to develop and evaluate a Motivational Interviewing Intervention designed to enhance the uptake of Pre-Exposure Prophylaxis (PrEP) among Latino men who have sex with men (MSM) in Puerto Rico. The intervention will focus on addressing barriers to PrEP access and adherence, utilizing motivational interviewing techniques to engage participants effectively. Eligible participants include HIV-negative or unknown status Latino MSM aged 21 and older who meet specific criteria for PrEP use. The study will be conducted at the University of Puerto Rico Medical Sciences Campus.

Why it matters

Potential benefit: If successful, this study could significantly increase PrEP uptake among Latino MSM, thereby reducing the risk of HIV transmission in this population.

How similar studies have gone: Other studies have shown success in using motivational interviewing to improve health outcomes, suggesting this approach may be effective in increasing PrEP uptake.

Who can join: the full rules

Show full inclusion / exclusion criteria
Latino MSM group - Inclusion Criteria:

* Biological male
* Age 21 or older
* Self-reported HIV negative or unknown status
* Not using PrEP (participants who have discontinued PrEP use can participate in the study), Spanish fluency (ability to write and read in Spanish)
* Presenting at least one of the eligibility criteria for PrEP as established by the CDC (including men who have had an infection (STI) in the past 6 months, HIV positive sexual partner)
* Access to a portable technology device (e.g., phone, tablet, laptop) or desktop computer access to internet connection

Exclusion Criteria:

* HIV positive individual
* Evidence of being under the effects of alcohol or drugs
* Indication of unstable or serious psychiatric symptoms
* Evidence of major cognitive impairment
* Inability to speak and read in Spanish

Healthcare Providers group - Inclusion Criteria:

* Age 21 or older
* Providing PrEP related health services at time of enrollment (e.g., case management, clinical services)
* Spanish fluency (ability to write and read in Spanish)

Exclusion Criteria:

* Evidence of being under the effects of alcohol or drugs
* Indication of unstable or serious psychiatric symptoms
* Evidence of major cognitive impairment
* Inability to speak and read in Spanish

Where it's running

  • University of Puerto Rico Medical Sciences Campus
    San Juan, Puerto Rico
    Recruiting

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.