Increasing enrollment of Black and Hispanic patients in cancer clinical trials
Working Through Outreach, Navigation and Digital Enabled Referral and Recruitment Strategies (ACT WONDER²S)
This study is trying to see if targeted outreach and support can help more Black and Hispanic patients join cancer clinical trials at Moffitt Cancer Center.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 7649 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | H. Lee Moffitt Cancer Center and Research Institute Academic / other |
| Locations | 1 site (Tampa, Florida) |
| Trial ID | NCT06560398 on ClinicalTrials.gov |
What this trial studies
This study aims to enhance the enrollment of Black and Hispanic patients in National Cancer Institute-sponsored therapeutic clinical trials at Moffitt Cancer Center through a multi-level intervention. It employs a stratified cluster randomized design, utilizing geospatial analytics to identify priority zones with high populations of these communities. The intervention includes outreach and education facilitated by community health educators, implicit bias training for healthcare providers, and the development of digitally enabled decision support tools. The effectiveness of this approach will be evaluated by comparing intervention and control groups within the identified priority zones.
Who should consider this trial
Good fit: Ideal candidates include Black and Hispanic community residents and physicians practicing in designated priority zones, as well as patients newly registered at Moffitt Cancer Center.
Not a fit: Patients outside the priority zones or those not newly registered at Moffitt Cancer Center may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could significantly improve access to cancer clinical trials for underrepresented populations, leading to better health outcomes.
How similar studies have performed: Other studies have shown success in increasing clinical trial enrollment through targeted outreach and education strategies, indicating that this approach has potential.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Community residents: Community residents may engage with various intervention components deployed in the intervention priority zones. * Community Physicians: may engage with various intervention components deployed in the intervention priority zones if they 1) practice medicine in one of the geographic priority zones. * Cancer Center Physicians: may engage with various intervention components if they 1) practice medicine at Moffitt. * Clinical Research Coordinators (CRC): may engage with various intervention components if they 1) work as a CRC at Moffitt and 2) coordinate/pre-screen patients for at least 1 therapeutic clinical trial at Moffitt. * Cancer Center Patients: may engage with various intervention components if they have an address that maps to an intervention priority zone and 2) are newly registered patients or new existing patients (NEPs). Exclusion Criteria: * Community residents, Community Physicians, Cancer Center Physicians, Clinical Research Coordinators, and Moffitt patients who do not meet the inclusion criteria.
Where this trial is running
Tampa, Florida
- Moffitt Cancer Center — Tampa, Florida, United States (Recruiting)
Study contacts
- Principal investigator: Susan Vadaparampil, PhD — Moffitt Cancer Center
- Study coordinator: Rossybelle Amorrortu, MPH
- Email: Rossybelle.Amorrortu@moffitt.org
- Phone: 813-745-4007
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.