Increased dietary fiber plus time‑restricted eating to lower cancer risk in adults with obesity
Examining the Independent and Combined Effects of Dietary Fiber and Time Restricted Eating on Indicators of Cancer Risk: the Fiber and Time Restricted Eating (F.I.T.) Study
This project tests whether adding more dietary fiber and using time‑restricted eating can lower cancer risk markers in adults with obesity who currently eat little fiber.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 90 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | University of Oklahoma Academic / other |
| Locations | 1 site (Columbus, Ohio) |
| Trial ID | NCT07219706 on ClinicalTrials.gov |
What this trial studies
This interventional study will compare combinations of two dietary approaches—raising fiber intake and adopting time‑restricted eating—delivered through group education and counseling. Eligible participants are adults aged 18 or older with BMI ≥30 kg/m2 who consume ≤15 g of fiber per day and who have a compatible smartphone for ecological momentary assessment. People with conditions that prevent fiber intake, limiting food allergies or intolerances, a positive eating‑disorder screen, current GLP‑1 receptor agonist use, or pregnancy/breastfeeding are excluded. The study will use app-based reporting and counseling to track behaviors and measure changes in biomarkers and diet-related behaviors linked to cancer risk and weight.
Who should consider this trial
Good fit: Adults aged 18 or older with obesity (BMI ≥30) who currently consume 15 g or less of fiber per day and can use a compatible smartphone are the intended participants.
Not a fit: People with inflammatory bowel disease or other diagnoses that preclude increased fiber, restrictive food allergies/intolerances, a positive eating‑disorder screen, current GLP‑1 receptor agonist use, or those who are pregnant, breastfeeding, or planning pregnancy may not benefit from this intervention.
Why it matters
Potential benefit: If successful, the combination could lower biomarkers of cancer risk and help with weight management and healthier eating habits.
How similar studies have performed: Prior research shows time‑restricted eating and higher‑fiber diets can improve weight and metabolic markers, but using them together specifically to reduce cancer risk is relatively novel and less tested.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * ≥18 age * Body mass index ≥30 kg/m2 * Dietary fiber intake ≤15 g/day * Compatible cell phone for use of ecological momentary assessment app Exclusion Criteria: * Self-reported diagnosis that precludes fiber intake (e.g., inflammatory bowel disease) * Food allergies or intolerances that limit ability to engage with the intervention * Positive screen on the SCOFF eating disorder screener39 * Current self-reported use of GLP-1 receptor agonists * Currently pregnant or breastfeeding, or planning to become pregnant
Where this trial is running
Columbus, Ohio
- University of Oklahoma Health Sciences — Columbus, Ohio, United States (Recruiting)
Study contacts
- Study coordinator: Ashlea Braun, PhD
- Email: ashlea-braun@ou.edu
- Phone: 15672401582
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.