Clinical trial Recruiting at 1 site Interventional Ages 18 and up

Increase resilience for lymphoma survivors after treatment

Official title: Increasing Resiliency Among Early Post-Treatment Lymphoma Survivors

Run by Massachusetts General Hospital · NCT07014293 · Data updated 2026-11-12

A mind-body group program is tested to see if it helps early post-treatment lymphoma survivors cope better than usual care.

Quick facts

Study typeInterventional
Ages18 Years and up
SexAll
Enrollment254 (estimated)
SponsorMassachusetts General Hospital
Academic / other
Drugs / interventionschemotherapy, immunotherapy, radiation
Locations1 site (Boston, Massachusetts)
StatusRecruiting
StartedSeptember 3, 2026
Main results expectedJuly 1, 2030
Study endsJuly 1, 2030
Registry record updatedSeptember 28, 2026
Trial IDNCT07014293 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults 18 years or older, English-speaking, who are at least 6 months post-diagnosis and have either ongoing treatment response or disease control within 2 years after completing treatment.

Probably not a fit

Individuals with uncontrolled or progressive lymphoma during the study or those unable to participate via telehealth may not benefit.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This randomized trial tests the SMART3RP-Lymphoma mind-body resilience program against enhanced usual care in 254 adults who are in early survivorship after lymphoma treatment. The intervention blends cognitive-behavioral, positive psychology, and relaxation techniques to improve coping with chronic stress related to survivorship. Outcomes focus on coping skills, with exploratory analyses looking at how factors like age, sex, race/ethnicity, and living situation may influence responses. The study is led by Massachusetts General Hospital and conducted within Mass General Brigham sites in Boston, MA. Results will inform whether structured psychosocial support can improve adjustment after lymphoma treatment.

Why it matters

Potential benefit: If successful, participants may experience improved coping and resilience during the transition to survivorship.

How similar studies have gone: Previous mind-body and resiliency programs have shown benefit in coping and stress management in cancer survivorship populations, supporting the approach's potential.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* English speaking adult (18 years or older at enrollment)
* Is at least 6 months post-diagnosis and a) is currently undergoing lymphoma treatment (includes surgery, chemotherapy/immunotherapy/radiation therapy, or other) with evidence of treatment response or disease control; or b) has completed lymphoma treatment (e.g., chemotherapy/immunotherapy/radiation therapy, surgery or other) within the past 2 years and has disease control at treatment completion; patients may still be on maintenance treatment to prolong disease control.

Exclusion Criteria:

* Has not initiated treatment for lymphoma.
* Has worsening, progressive, or uncontrolled disease that is not responding to treatment.
* Active Psychiatric, medical or cognitive comorbidity as determined by site PI or treating clinician
* Unwilling or unable to participate using telehealth platform

Where it's running

  • Mass General Brigham
    Boston, Massachusetts, United States
    Recruiting

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.