Improving Vitamin D Levels with Different Treatments

Different Kinds of Vitamin D Intake and Its Metabolites: Blood Levels and Bone Mineral Density. A Randomized Clinical Trial.

Not applicable Interventional Azienda Ospedaliero-Universitaria Consorziale Policlinico di Bari · NCT06138249

This study is testing which of two types of Vitamin D supplements works best for people with low Vitamin D levels to help improve their health.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment90 (estimated)
Ages18 Years to 80 Years
SexAll
SponsorAzienda Ospedaliero-Universitaria Consorziale Policlinico di Bari Academic / other
Locations1 site (Bari)
Trial IDNCT06138249 on ClinicalTrials.gov

What this trial studies

This clinical trial investigates the effectiveness of two forms of Vitamin D supplementation, Calcifediol and Cholecalciferol, in patients suffering from hypovitaminosis D. Participants are randomly assigned to one of three treatment groups: one receiving Calcifediol monthly, another receiving Cholecalciferol bi-weekly, and a third receiving daily Calcifediol drops. After one month of treatment, serum levels of Vitamin D will be measured to determine the most effective dosage. The study aims to optimize Vitamin D intake for better health outcomes.

Who should consider this trial

Good fit: Ideal candidates for this study are individuals diagnosed with hypovitaminosis D, characterized by serum levels below 20 ng/mL.

Not a fit: Patients with osteoporosis or those suffering from renal or hepatic diseases may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved Vitamin D levels in patients, enhancing their overall health and well-being.

How similar studies have performed: Other studies have shown varying success with Vitamin D supplementation, but this specific comparison of Calcifediol and Cholecalciferol is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Hypovitaminosis D (\<20ng/mL)

Exclusion Criteria:

* Osteoporosis (T score \<-2.5SD)
* Renal or hepatic diseases

Where this trial is running

Bari

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Hypovitaminosis D
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.