Improving survival rates for cardiac arrest in residential areas with mobile responders
Official title: A Cluster Randomized Clinical Trial of Strategic AED Deployment in High-risk Residential Areas Combined With Activation of Local Residents
Run by Emergency Medical Services, Capital Region, Denmark · NCT04446585 · Data updated 2026-11-12
This study is testing whether training local residents to use defibrillators and increasing their availability can help save more lives after cardiac arrests in neighborhoods.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 8 Years and up |
| Sex | All |
| Enrollment | 260 (estimated) |
| Sponsor | Emergency Medical Services, Capital Region, Denmark Government |
| Locations | 1 site (Ballerup Municipality, The Capital Region) |
| Status | Recruiting |
| Started | December 1, 2021 |
| Main results expected | January 2027 |
| Study ends | January 2027 |
| Registry record updated | September 15, 2023 |
| Trial ID | NCT04446585 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are individuals who experience a witnessed, non-traumatic cardiac arrest in the designated residential areas.
✕Probably not a fit
Patients who experience cardiac arrests in nursing homes or those not treated by emergency medical services will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study focuses on enhancing bystander defibrillation rates during out-of-hospital cardiac arrests in residential areas with high incidence. The intervention involves deploying Automated External Defibrillators (AEDs) and training local residents to act as citizen responders. By increasing community involvement and access to AEDs, the study aims to improve the rates of defibrillation and survival within 30 days following a cardiac arrest. The initiative targets densely populated areas to maximize impact and effectiveness.
Why it matters
Potential benefit: If successful, this approach could significantly increase survival rates for individuals experiencing cardiac arrest in residential settings.
How similar studies have gone: Other studies have shown promising results in increasing survival rates through community-based interventions and training, indicating that this approach has potential for success.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * All witnessed cardiac arrests recognized registered in the Danish Cardiac Arrest Registry occurring within the study sites. This excludes non witnessed cardiac arrests. * Witnessed cardiac arrest * Non-traumatic etiology, this excludes intoxication, drowning or suicide. Exclusion Criteria: * Cardiac arrest occurring in a nursing home * Cardiac arrest not treated by the EMS due to ethical reasons or obvious signs of death * Not true cardiac arrest (suspected, but not verified) * Cardiac arrests witnessed by the emergency medical personnel
Where it's running
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Emergency Medical Services Copenhagen
Ballerup Municipality, The Capital Region, Denmark Recruiting
Study contacts
- Principal investigator: Fredrik Folke, MD, PhD — EMS Copenhagen
- Study coordinator: Anne J Jørgensen, MD
- Email: anne.juul.joergensen.02@regionh.dk
- Phone: +45 60 62 91 14
Similar studies
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Early double sequential defibrillation for cardiac arrest outside the hospital
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This study is testing if a special emergency treatment called prehospital extracorporeal cardiopulmonary resuscitation (ECPR) can help people who have a cardiac arrest outside of the hospital survive better and have better brain function compared to those who only get treatment in the hospital.
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Initial double sequential defibrillation for out-of-hospital ventricular fibrillation
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.