Improving surgical techniques for thyroid tumors and understanding cancer progression
Improvements in Thyroid Tumor Surgery and the Prognosis, Diagnosis, Recurrence and Metastasis of Patients
This study is testing a new way to perform thyroid surgery to see if it can make the operation quicker and safer for patients while also looking at thyroid tissues to better understand how thyroid cancer develops and spreads.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 170 (estimated) |
| Ages | 18 Years to 75 Years |
| Sex | All |
| Sponsor | Second Affiliated Hospital of Xi'an Jiaotong University Academic / other |
| Locations | 1 site (Xi'an, Shaanxi) |
| Trial ID | NCT06468696 on ClinicalTrials.gov |
What this trial studies
This research investigates the clinical outcomes of modified surgical techniques in thyroid surgery, specifically focusing on the omission of the cervical linea alba suture during transthoracic endoscopic thyroidectomy. The study aims to evaluate the safety and feasibility of this approach in reducing operation time, postoperative pain, and complications. Additionally, it involves the collection of normal thyroid tissues, benign and malignant tumors, and lymph nodes to better understand the mechanisms of thyroid cancer initiation, progression, metastasis, and recurrence. By combining clinical outcomes with basic research, the study seeks to enhance surgical methods and patient prognosis.
Who should consider this trial
Good fit: Ideal candidates include patients scheduled for transthoracic endoscopic thyroidectomy with confirmed benign or malignant thyroid tumors and no signs of extrathyroidal invasion.
Not a fit: Patients who have previously undergone transthoracic endoscopic thyroidectomy or have contraindications for general anesthesia may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved surgical outcomes and reduced complications for patients undergoing thyroid surgery.
How similar studies have performed: While there is ongoing research in minimally invasive thyroid surgery, this specific approach of omitting sutures during the procedure is novel and has not been extensively tested.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Perform transthoracic endoscopic thyroidectomy via breast approach; 2. Postoperative pathology confirms benign or malignant thyroid tumors; 3. Preoperative thyroid ultrasound or cervical CT suggests no extrathyroidal invasion or distant metastasis of the tumor; 4. No contraindications for general anesthesia; 5. Patients with cosmetic requirements. Exclusion Criteria: 1. Underwent transthoracic endoscopic thyroidectomy; 2. Postoperative pathology confirmed as benign or malignant thyroid tumors; 3. Preoperative thyroid ultrasound or neck CT suggested no extraglandular invasion or distant metastasis of the tumor; 4. No contraindications to general anesthesia; 5. Patients with cosmetic demands.
Where this trial is running
Xi'an, Shaanxi
- Xi'an Jiaotong University Second Affiliated Hospital — Xi'an, Shaanxi, China (Recruiting)
Study contacts
- Principal investigator: Zhidong Wang — Xi'an Jiaotong University Second Affiliated Hospital
- Study coordinator: Zhidong Wang, Professor
- Email: xawzd@163.com
- Phone: +86 138 9182 3580
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.