Improving surgery outcomes for sarcopenic patients with pancreatic cancer
Prehabilitaion Program for Sarcopenic Patients Prior to Pancreaticoduodenectomy for Periampullary Malignant Tumors
This study is testing a special exercise program for patients with low muscle mass who are about to have surgery for pancreatic cancer to see if it helps them recover better and have fewer complications.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 158 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | University Hospital, Lille Academic / other |
| Locations | 1 site (Lille) |
| Trial ID | NCT04469504 on ClinicalTrials.gov |
What this trial studies
This study focuses on preoperative prehabilitation for patients with sarcopenia who are scheduled to undergo pancreatic surgery for cancer. The approach involves a rehabilitation program aimed at enhancing muscular and functional reserves before surgery, which is hypothesized to reduce postoperative complications. Given the high prevalence of sarcopenia in pancreatic cancer patients, this intervention seeks to improve overall surgical outcomes and survival rates. The study will assess the effectiveness of this prehabilitation strategy in a clinical setting.
Who should consider this trial
Good fit: Ideal candidates for this study are adults with sarcopenic status who are scheduled for pancreaticoduodenectomy due to cancer.
Not a fit: Patients under 18 years old, those with significant cardiovascular or vascular diseases, or individuals unable to participate in physical exercise may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could significantly reduce postoperative complications and improve recovery for sarcopenic patients undergoing pancreatic surgery.
How similar studies have performed: While the concept of prehabilitation is gaining traction, this specific approach targeting sarcopenic patients undergoing pancreatic surgery is relatively novel and has not been extensively tested in prior studies.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients undergoing pancreaticoduodenectomy for cancer * Sarcopenic status Exclusion Criteria: * Age younger than 18 years * Medical contraindications including cardiovascular disease or clinically significant vascular disease * Physical inability to exercise * Emergent surgery
Where this trial is running
Lille
- Hop Claude Huriez Chu Lille — Lille, France (Recruiting)
Study contacts
- Principal investigator: Mehdi ELAMRANI, MD — University Hospital, Lille
- Study coordinator: Mehdi ELAMRANI, MD
- Email: mehdi.elamrani@chru-lille.fr
- Phone: 0320444465
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.