Improving stent placement in heart procedures
Official title: Optimization of Percutaneous Coronary Intervention After Stent Implantation With Liberal Use of High-pressure Non-compliant Balloon Post-dilatation Versus Contemporary Practice
Run by Cathreine BV · NCT06558474 · Data updated 2026-11-12
This study is trying to see if using a special technique during stent placement can help people with heart problems avoid complications and improve their treatment outcomes.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 12000 (estimated) |
| Sponsor | Cathreine BV Academic / other |
| Locations | 1 site (Eindhoven, North Brabant) |
| Status | Recruiting |
| Started | September 1, 2023 |
| Main results expected | June 1, 2025 |
| Study ends | May 1, 2026 |
| Registry record updated | August 7, 2025 |
| Trial ID | NCT06558474 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are patients over 18 years old undergoing PCI for any indication.
✕Probably not a fit
Patients who have undergone multiple PCIs within the last 365 days will not benefit from this study as only their first procedure will be included.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study focuses on optimizing the outcomes of percutaneous coronary interventions (PCI) by employing a liberal post-dilatation strategy during stent deployment. It utilizes data from the Netherlands Heart Registration, which collects comprehensive information on cardiac procedures, to analyze the effects of post-dilatation on stent expansion and its subsequent impact on preventing complications like stent thrombosis and restenosis. The study aims to clarify the role of post-dilatation in routine clinical practice, addressing a gap in existing evidence regarding its benefits. By evaluating a large dataset, the study seeks to provide insights into best practices for stent optimization.
Why it matters
Potential benefit: If successful, this approach could lead to improved long-term outcomes for patients undergoing PCI, reducing the risk of complications associated with stent placement.
How similar studies have gone: While there is limited evidence on the routine use of post-dilatation, similar studies have explored its effects, indicating a need for further investigation in this area.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * All patients \>18 years old who undergo PCI for any indication are included in the register of the Netherlands Heart Registration and therefore included in the final analysis of this project Exclusion Criteria: \- If a patient has multiple PCIs within 365 days, only the first procedure is included.
Where it's running
-
Catharina Hospital
Eindhoven, North Brabant, Netherlands Recruiting
Study contacts
- Study coordinator: K Teeuwen, MD, PhD
- Email: koen.teeuwen@catharinaziekenhuis.nl
- Phone: + 31 040 239 9111
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.