Clinical trial Recruiting at 1 site Observational Ages 18 and up

Improving stent placement in heart procedures

Official title: Optimization of Percutaneous Coronary Intervention After Stent Implantation With Liberal Use of High-pressure Non-compliant Balloon Post-dilatation Versus Contemporary Practice

Run by Cathreine BV · NCT06558474 · Data updated 2026-11-12

This study is trying to see if using a special technique during stent placement can help people with heart problems avoid complications and improve their treatment outcomes.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment12000 (estimated)
SponsorCathreine BV
Academic / other
Locations1 site (Eindhoven, North Brabant)
StatusRecruiting
StartedSeptember 1, 2023
Main results expectedJune 1, 2025
Study endsMay 1, 2026
Registry record updatedAugust 7, 2025
Trial IDNCT06558474 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are patients over 18 years old undergoing PCI for any indication.

Probably not a fit

Patients who have undergone multiple PCIs within the last 365 days will not benefit from this study as only their first procedure will be included.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study focuses on optimizing the outcomes of percutaneous coronary interventions (PCI) by employing a liberal post-dilatation strategy during stent deployment. It utilizes data from the Netherlands Heart Registration, which collects comprehensive information on cardiac procedures, to analyze the effects of post-dilatation on stent expansion and its subsequent impact on preventing complications like stent thrombosis and restenosis. The study aims to clarify the role of post-dilatation in routine clinical practice, addressing a gap in existing evidence regarding its benefits. By evaluating a large dataset, the study seeks to provide insights into best practices for stent optimization.

Why it matters

Potential benefit: If successful, this approach could lead to improved long-term outcomes for patients undergoing PCI, reducing the risk of complications associated with stent placement.

How similar studies have gone: While there is limited evidence on the routine use of post-dilatation, similar studies have explored its effects, indicating a need for further investigation in this area.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* All patients \>18 years old who undergo PCI for any indication are included in the register of the Netherlands Heart Registration and therefore included in the final analysis of this project

Exclusion Criteria:

\- If a patient has multiple PCIs within 365 days, only the first procedure is included.

Where it's running

  • Catharina Hospital
    Eindhoven, North Brabant, Netherlands
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.