Improving smoking cessation through telehealth in primary care

Hybrid Type 1 Effectiveness-Implementation Trial of a Proactive Smoking Cessation Electronic Visit for Scalable Delivery Via Primary Care

Not applicable Interventional Medical University of South Carolina · NCT05493254

This study is testing if an online visit can help people quit smoking better than regular care by offering support and possibly medication.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment672 (estimated)
Ages18 Years and up
SexAll
SponsorMedical University of South Carolina Academic / other
Locations1 site (Charleston, South Carolina)
Trial IDNCT05493254 on ClinicalTrials.gov

What this trial studies

This study evaluates the effectiveness of an electronic visit (e-visit) designed to assist individuals in quitting smoking. Participants will be randomly assigned to either receive the e-visit, which includes a questionnaire about their smoking habits and preferences for cessation medications, or to a control group receiving standard care. The study will track participants over 24 weeks, collecting data through questionnaires and breath samples at four different time points. The e-visit may lead to a prescription for smoking cessation medication, although taking medication is not mandatory.

Who should consider this trial

Good fit: Ideal candidates are adults aged 18 and older who smoke at least one cigarette per day and have been smoking for the past six months.

Not a fit: Patients who have used FDA-approved cessation medications in the last week will not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could significantly enhance smoking cessation rates among participants.

How similar studies have performed: Other studies have shown promising results using telehealth interventions for smoking cessation, indicating that this approach is supported by prior research.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. current smoking, defined as 1+ cigarettes/day, for 20+ days out of the last 30 for the last 6+ months
2. age 18+
3. enrolled in MyChart or willing to enroll
4. possess a valid e-mail address that is checked daily
5. owner of an iOS or Android smartphone to provide remote CO
6. have a valid mailing address
7. English fluency

Exclusion Criteria:

1\) Use of an FDA-approved cessation medication in the last 7 days

Where this trial is running

Charleston, South Carolina

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Smoking Cessation
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.