Improving smoking cessation support for people living with HIV

Optimizing Tobacco Treatment Delivery for People Living With HIV

Not applicable Interventional Medical University of South Carolina · NCT05019495

This study is testing a new way of helping people with HIV quit smoking by comparing regular support to a more proactive approach to see which one works better.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment231 (estimated)
Ages21 Years and up
SexAll
SponsorMedical University of South Carolina Academic / other
Locations1 site (Charleston, South Carolina)
Trial IDNCT05019495 on ClinicalTrials.gov

What this trial studies

This study evaluates a proactive model of provider contact to deliver smoking cessation support for individuals living with HIV, comparing it to standard care. Participants will be randomly assigned to receive either Treatment As Usual (TAU) or the Proactive Outreach with Medication Opt-out for Tobacco Treatment Engagement (PrOMOTE). The primary goal is to assess the effectiveness of these approaches in increasing smoking cessation rates and quit attempts at a 12-week follow-up. Additionally, the study will explore barriers and facilitators to implementing the PrOMOTE model and its impact on health outcomes related to HIV.

Who should consider this trial

Good fit: Ideal candidates for this study are individuals aged 21 and older who are currently diagnosed with HIV and are current smokers.

Not a fit: Patients who are currently participating in other tobacco treatment programs or using cessation medications will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could significantly improve smoking cessation rates among people living with HIV, leading to better health outcomes.

How similar studies have performed: Other studies have shown promise in using proactive outreach models for smoking cessation, suggesting potential success for this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age 21 and older
* Current diagnosis of HIV
* Current smoker (defined as self-report of current smoking)
* Willing to be randomized
* English speaking

Exclusion Criteria:

* Currently taking part in any other tobacco treatment program or using cessation medication (i.e., taking nicotine replacement therapy or other cessation medications, enrolled in the Quitline, or in another study)
* Currently imprisoned
* Pregnant women
* Non-English speaking persons

Where this trial is running

Charleston, South Carolina

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions HivSmoking, CigaretteSmoking
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.