Clinical trial Recruiting at 2 sites Observational Ages 40 to 90

Improving rehabilitation for veterans after knee surgery

Official title: Improving Rehabilitation for Veterans After Total Knee Arthroplasty Using Individualized Recovery Trajectories

Run by VA Office of Research and Development · NCT05288803 · Data updated 2026-11-12

This study is testing a new tool to help veterans recover better after knee surgery by personalizing their rehabilitation based on their individual needs and goals.

Quick facts

Study typeObservational
Ages40 Years to 90 Years
SexAll
Enrollment200 (estimated)
SponsorVA Office of Research and Development
Federal
Locations2 sites (Aurora, Colorado and 1 other locations)
StatusRecruiting
StartedApril 1, 2022
Main results expectedMarch 31, 2027
Study endsJune 30, 2027
Registry record updatedOctober 8, 2026
Trial IDNCT05288803 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are veterans who have undergone total knee arthroplasty and are seeking outpatient rehabilitation within three weeks post-surgery.

Probably not a fit

Patients who received postoperative rehabilitation in home health or skilled nursing facilities, or those aged under 40 or over 90, may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study examines a new clinical decision support tool designed to enhance rehabilitation for veterans recovering from total knee arthroplasty (TKA). The tool aims to personalize rehabilitation treatments based on individual patient needs, goals, and preferences, rather than applying a one-size-fits-all approach. By analyzing recovery data from similar historical patients, the tool predicts recovery trajectories, allowing clinicians to allocate resources more effectively and identify veterans at risk for suboptimal outcomes. This approach seeks to improve functional recovery while reducing the number of physical therapy visits required post-surgery.

Why it matters

Potential benefit: If successful, this tool could lead to more efficient and effective rehabilitation for veterans, improving their recovery outcomes after knee surgery.

How similar studies have gone: Other studies have shown promise in using personalized rehabilitation approaches, but this specific clinical decision support tool is a novel application in the context of TKA rehabilitation.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

-Veterans who have undergone total knee arthroplasty who present for outpatient rehabilitation treatment at the participating clinics within three weeks of surgery

Exclusion Criteria:

\- postoperative rehabilitation treatment received in the home health or skilled nursing

Where it's running

  • Rocky Mountain Regional VA Medical Center, Aurora, CO
    Aurora, Colorado, United States
    Recruiting
  • VA Pittsburgh Healthcare System University Drive Division, Pittsburgh, PA
    Pittsburgh, Pennsylvania, United States
    Recruiting

Study contacts

  • Principal investigator: Jennifer E. Stevens-Lapsley, PhD — Rocky Mountain Regional VA Medical Center, Aurora, CO
  • Study coordinator: Jennifer E Stevens-Lapsley, PhD
  • Email: Jennifer.Stevens-Lapsley@va.gov
  • Phone: (303) 949-9304

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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  • DoACs vs LMWH for blood flow after knee replacement

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    Recruiting Military Hospital of Tunis · Tunis, Tunis Governorate · NCT07869615

  • Branched chain amino acids after knee replacement to help muscle

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    Recruiting at 2 sites Phase 4 Seoul National University Hospital · Seongnam-si, Gyeonggi-do and 2 other locations · NCT07634523

  • Cryotherapy to Cut Opioid Use After Knee Replacement

    This trial tests whether compressive cryotherapy with a Game Ready device can lower opioid use and improve recovery after total knee replacement in adults 60–80.

    Recruiting Hospital Italiano de Buenos Aires · Buenos Aires, Buenos Aires · NCT07630337

  • Early cognitive changes after same-day hip or knee replacement

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    Recruiting Odense University Hospital · Svendborg · NCT07598552

  • Preoperative Genicular Nerve Block for Knee Replacement

    This study tests whether giving a genicular nerve block before knee replacement can reduce pain after surgery and lower opioid use.

    Recruiting Helse Møre og Romsdal HF · Hjelset, Møre og Romsdal · NCT07589127

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.