Improving recovery in elderly surgical patients with nutrition and oral care

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the effectiveness of perioperative oral decontamination and immunonutrition supplementation in reducing postoperative complications among elderly patients undergoing elective non-cardiac surgeries. It is a prospective, single-center, randomized controlled trial that will recruit patients aged 65 and older, who will be divided into four groups to receive different combinations of oral care and nutrition interventions. The aim is to assess whether these interventions can improve patient outcomes and reduce the risk of complications related to surgery.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. age≥65 years;
2. undergoing non-cardiac surgery (expected duration \>2 hours);
3. scheduled for general anesthesia and endotracheal intubation;
4. ASA classification I-IV;
5. with intermediate to high risk of respiratory complications assessed by ARISCAT score (Assess Respiratory Risk in Surgical Patients in Catalonia);
6. inform consent obtained

Exclusion Criteria:

1. emergency surgery;
2. preoperative pneumonia;
3. allergic to chlorhexidine;
4. severe hepatic/renal dysfunction, incapable of oral feeding, with autoimmune diseases, taking immunosuppressant or immunoregulation medications, or with other contraindication to immunonutrition supplementation;
5. expected intervention of immunonutrition\<3 days.

Where it's running

• Peking Union Medical College Hospital
  Beijing, China Recruiting

Study contacts

• Principal investigator: Yuguang Huang — Peking Union Medical College Hospital (CAMS)
• Study coordinator: Lu Che, MD
• Email: tracymaobao@126.com
• Phone: 69152020

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.