Improving prevention and treatment strategies for cardiomyopathy patients
Official title: Risk Stratification and New Early Prevention and Treatment Strategies for Patients With Cardiomyopathy (STRENGTH Trial): a National Multi-center, Retrospective-prospective, Cohort Study
Run by First Affiliated Hospital Xi'an Jiaotong University · NCT06352320 · Data updated 2026-11-12
This study is trying to gather information from cardiomyopathy patients to find better ways to prevent and treat their condition.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 80 Years |
| Sex | All |
| Enrollment | 500 (estimated) |
| Sponsor | First Affiliated Hospital Xi'an Jiaotong University Academic / other |
| Locations | 1 site (Xi'an, Shaanxi) |
| Status | Recruiting |
| Started | May 9, 2024 |
| Main results expected | August 31, 2030 |
| Study ends | August 31, 2032 |
| Registry record updated | July 12, 2024 |
| Trial ID | NCT06352320 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are adults over 18 years old with a confirmed diagnosis of cardiomyopathy.
✕Probably not a fit
Patients with incomplete clinical data or those who do not consent to participate will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to create a natural population cohort of patients with various types of cardiomyopathy by enrolling participants from multiple centers. It will collect clinical data and biological samples from surgical patients to develop a prognostic system for cardiomyopathy. The study seeks to optimize risk stratification and explore new strategies for early prevention and treatment, ultimately enhancing the diagnosis and treatment efficiency for cardiomyopathy patients.
Why it matters
Potential benefit: If successful, this study could lead to improved early prevention and treatment strategies for patients with cardiomyopathy.
How similar studies have gone: While there have been studies focusing on cardiomyopathy, this approach of creating a comprehensive prognostic system is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age \>18 years old. * The diagnosis of cardiomyopathy was confirmed by cardiac ultrasound, electrocardiogram, magnetic resonance angiography, pathological examination and gene sequencing. * Patients or their families agreed to participate in the study and authorized informed consent. Exclusion Criteria: * Incomplete clinical data. * Do not agree to the inclusion or refuse to authorize the informed consent.
Where it's running
-
First Affiliated Hospital of Xi'an Jiantong University
Xi'an, Shaanxi, China Recruiting
Study contacts
- Principal investigator: Yang Yan — First Affiliated Hospital Xi'an Jiaotong University
- Study coordinator: Yang Yan
- Email: yangyan3@xjtu.edu.cn
- Phone: +862985323869
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Myocardial Energetics Across Cardiovascular Disease Spectrum Using 31P-MRS
Researchers are testing whether phosphorus-31 magnetic resonance spectroscopy (31P-MRS) can map heart energy metabolism across healthy people and patients with various heart conditions.
-
Liver and Coagulation Markers in ATTR Cardiac Amyloidosis
This study tests liver function and blood-clotting markers in people with ATTR-CA to see if they reflect disease severity and progression.
-
RHYthm and Myocardial Function Relationship in Heart Disease
This study tests how heart rhythm patterns relate to heart muscle function in adults with arrhythmias or cardiomyopathy.
-
Multimodal analysis of heart biopsy samples
This project will take one extra small heart biopsy during a clinically needed procedure to test whether detailed molecular and immune analyses can find disease-specific signatures in adults with cardiomyopathies, myocarditis, cardiac amyloidosis, or after heart transplant.
-
Electrophysiological mapping to predict sudden cardiac death risk
It will test whether detailed electrical mapping of the left ventricle can better predict dangerous ventricular arrhythmias in adults with ischemic or non-ischemic cardiomyopathy and LVEF under 50% who are not already ICD candidates.
-
Using retinal photographs to assess cardiovascular disease risk in heart failure patients
This study is testing if looking at retinal photographs can help predict the risk of heart problems in people who have recently been diagnosed with heart failure.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.