Improving PrEP access for women who inject drugs

Implementation of PrEP for Women Who Inject Drugs Through Practice Facilitation in Primary and Reproductive Health Care

Not applicable Interventional University of Pennsylvania · NCT05360849

This study is testing ways to make it easier for women who inject drugs to get PrEP, a medication that helps prevent HIV, by working with healthcare providers and clinics to improve their services.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment130 (estimated)
Ages18 Years and up
SexFemale
SponsorUniversity of Pennsylvania Academic / other
Locations1 site (Philadelphia, Pennsylvania)
Trial IDNCT05360849 on ClinicalTrials.gov

What this trial studies

This research focuses on enhancing the delivery of pre-exposure prophylaxis (PrEP) to women who inject drugs, a group at high risk for HIV infection. By gathering insights from women who inject drugs, healthcare providers, and clinic leadership, the study aims to identify barriers and facilitators in the current healthcare system. The intervention involves Practice Facilitation, which provides clinics with technical assistance and support to implement effective PrEP delivery strategies. The ultimate goal is to reduce new HIV infections among this vulnerable population by improving access to preventive care.

Who should consider this trial

Good fit: Ideal candidates for this study are women who inject drugs and are at risk for HIV infection.

Not a fit: Patients who do not inject drugs or are not at risk for HIV may not benefit from this study.

Why it matters

Potential benefit: If successful, this initiative could significantly increase PrEP uptake among women who inject drugs, thereby reducing their risk of acquiring HIV.

How similar studies have performed: Other studies have shown success in implementing similar interventions to improve healthcare delivery for high-risk populations, indicating potential for positive outcomes in this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

To be included in the pilot test of Practice Facilitation, clinics must:

* Complete prior leadership and provider surveys
* Have 50 or more clinic visits with women who inject drugs in the past year
* Have 3 or more clinicians who provide primary and/or reproductive healthcare
* Have leadership willing to participate

Exclusion Criteria:

* None

Where this trial is running

Philadelphia, Pennsylvania

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions HIVIntravenous Substance AbuseWomen's HealthOrganization and AdministrationPrimary PreventionImplementation Science
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.