Improving physical activity in older adults living with HIV

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial aims to evaluate three different interventions designed to enhance physical activity among older adults living with HIV. The interventions include physical activity coaching, cognitive behavioral therapy to address barriers such as low motivation and chronic pain, and a Fitbit-based social support system. The primary outcome measured will be the number of steps taken per day, which will help determine the most effective components for a comprehensive behavioral intervention. The study utilizes the Multiphase Optimization Strategy (MOST) framework to develop and optimize these interventions for practical application in primary care settings.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. HIV positive: defined by HIV antibody, detectable HIV RNA in plasma, or a note from the participant's HIV care provider.
2. Must be on continuous antiretroviral therapy (ART) for \> 3 months, as assessed via self-report.
3. Low PA: defined as self-report of \< 90 minutes of moderate-vigorous PA (MVPA) per week in the previous 3 months AND less than 14 hours per week of sustained walking in the previous 4 weeks.
4. Medically cleared for moderate PA. If participants report a) a history of cardiovascular disease including known coronary artery disease, peripheral vascular disease, heart failure, or stroke; or b) chest pain, shortness of breath, or dizziness or syncope either at rest or during activity in the past 3 months, then they must have medical clearance by a physician or primary care provider.
5. Age 50 years or older.
6. Proficiency in English: sufficient to engage in informed consent, understand assessments and materials provided, and engage and use Fitbit application (all materials provided in English).
7. Capacity to consent, documented by acceptable answers in a consent "teach-back" process.
8. Score of greater than 16 on the MOCA
9. Able to ambulate without assistive devices
10. Ability to use the FitBit application, as demonstrated to study staff.

Exclusion Criteria:

* Exclusion Criteria

  1. Medical conditions or physical or neurocognitive limitations that interfere with PA or study participation.
  2. Hazardous substance use, assessed via a score ≥15 on the Alcohol Use Disorders Identification Test (AUDIT) or ≥6 on the Drug Abuse Screening Test (DAST).

Where it's running

• Hennepin Healthcare Research Institute
  Minneapolis, Minnesota, United States Recruiting
• Brown University Health
  Providence, Rhode Island, United States Recruiting

Study contacts

• Principal investigator: Lisa Uebelacker, PhD — Butler Hospital
• Study coordinator: Bailey O'Keeffe, MS
• Email: bokeeffe@butler.org
• Phone: 401-455-6219

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Motivating Activity Through Text Messages to Increase Movement

  This trial tests whether different motivational text messages can help adults aged 40+ move more, by tracking steps and activity over 6 months.

  Recruiting University of Michigan · Ann Arbor, Michigan · NCT07593677

• Using robots to help older adults become more physically active

  This study is testing whether using robots can help older adults become more active by changing their automatic thoughts about physical activity.

  Recruiting University of Ottawa · Ottawa, Ontario · NCT06843161

• Identifying challenges to healthy aging in older adults with HIV

  This study is trying to understand frailty in older adults with HIV and see if personalized activity and nutrition plans can help improve their health.

  Recruiting Wake Forest University Health Sciences · Winston-Salem, North Carolina · NCT05858034

• Personalized exercise program for cardiac outpatients

  This study is testing a personalized exercise program to see if it helps people with stable heart conditions improve their fitness and quality of life over time.

  Recruiting Università degli Studi di Ferrara · Ferrara, Ferrara · NCT05817305

• Examining health impacts of past sports injuries and inactivity

  This study is trying to see how past sports injuries and being inactive affect the long-term health of former athletes compared to non-athletes.

  Recruiting Marquette University · Milwaukee, Wisconsin · NCT05344001

• Investigating the effects of aging on insulin resistance and obesity

  This study is testing how physical activity can help older adults aged 60-80 improve their insulin sensitivity and manage obesity as they age.

  Recruiting University of Lausanne · Bern and 1 other locations · NCT01224886

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.