Improving pain management for patients on long-term opioid therapy
Official title: Improved Treatment for Patients With Long-term Opioid Therapy for Non-cancer Pain in Primary Care (Opi-Prim)
Run by Uppsala County Council, Sweden · NCT06856733 · Data updated 2026-11-12
This study is testing a new team-based approach to help people on long-term opioid therapy manage their chronic pain better than the usual care they currently receive.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 70 Years |
| Sex | All |
| Enrollment | 110 (estimated) |
| Sponsor | Uppsala County Council, Sweden Government |
| Locations | 4 sites (Gävle, Gävleborg County and 3 other locations) |
| Status | Recruiting |
| Started | March 10, 2025 |
| Main results expected | June 30, 2028 |
| Study ends | December 31, 2028 |
| Registry record updated | September 30, 2026 |
| Trial ID | NCT06856733 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are patients who have been prescribed opioids for chronic pain for at least 90 days in the past year.
✕Probably not a fit
Patients who are not currently using opioids, have severe cognitive dysfunction, or are using opioids for cancer pain may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This clinical trial aims to enhance pain management for patients on long-term opioid therapy (LTOT) for chronic non-cancer pain in primary care by implementing a new person-centred and team-based approach. The study will compare this innovative approach to usual care to assess its effectiveness in reducing pain interference. Participants will undergo a thorough assessment involving multiple healthcare professionals, followed by a tailored treatment plan. The goal is to optimize care and minimize inappropriate opioid use through a collaborative healthcare model.
Why it matters
Potential benefit: If successful, this approach could lead to better pain management and reduced reliance on opioids for patients with chronic non-cancer pain.
How similar studies have gone: While the specific approach of this study is novel, there have been successful examples of multi-professional interventions in managing chronic non-cancer pain internationally.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Having received the equivalent of 90 days or more prescription of opioids for chronic pain made by the general practitioner during the recent 12 months * Able to speak Swedish or English Exclusion Criteria: * Having been referred to a pain clinic (either at hospital or multimodal rehabilitation in primary care) within the last 6 months * No current opioid use, severe cognitive dysfunction, e.g., suicidal ideation, psychotic symptoms, or dementia, that prevents informed consent. * Using their opioids for cancer pain
Where it's running
-
Region Uppsala
Uppsala, Uppsala County, Sweden Recruiting -
Region Örebro Län
Örebro, Örebro County, Sweden Recruiting -
Region Gävleborg
Gävle, Gävleborg County, Sweden Not yet recruiting -
Region Sörmland
Strängnäs, Södermanland County, Sweden Not yet recruiting
Study contacts
- Study coordinator: Magnus Peterson, PhD, MD
- Email: magnus.peterson@regionuppsala.se
- Phone: +46702882768
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.