Improving pain management for patients on long-term opioid therapy

Improved Treatment for Patients With Long-term Opioid Therapy for Non-cancer Pain in Primary Care (Opi-Prim)

Not applicable Interventional Uppsala County Council, Sweden · NCT06856733

This study is testing a new team-based approach to help people on long-term opioid therapy manage their chronic pain better than the usual care they currently receive.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment110 (estimated)
Ages18 Years to 70 Years
SexAll
SponsorUppsala County Council, Sweden Government
Locations3 sites (Strängnäs, Sörmland and 2 other locations)
Trial IDNCT06856733 on ClinicalTrials.gov

What this trial studies

This clinical trial aims to enhance pain management for patients on long-term opioid therapy (LTOT) for chronic non-cancer pain in primary care by implementing a new person-centred and team-based approach. The study will compare this innovative approach to usual care to assess its effectiveness in reducing pain interference. Participants will undergo a thorough assessment involving multiple healthcare professionals, followed by a tailored treatment plan. The goal is to optimize care and minimize inappropriate opioid use through a collaborative healthcare model.

Who should consider this trial

Good fit: Ideal candidates are patients who have been prescribed opioids for chronic pain for at least 90 days in the past year.

Not a fit: Patients who are not currently using opioids, have severe cognitive dysfunction, or are using opioids for cancer pain may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could lead to better pain management and reduced reliance on opioids for patients with chronic non-cancer pain.

How similar studies have performed: While the specific approach of this study is novel, there have been successful examples of multi-professional interventions in managing chronic non-cancer pain internationally.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Having received the equivalent of 90 days or more prescription of opioids for chronic pain made by the general practitioner during the recent 12 months
* Able to speak Swedish or English

Exclusion Criteria:

* Having been referred to a pain clinic (either at hospital or multimodal rehabilitation in primary care) within the last 6 months
* No current opioid use, severe cognitive dysfunction, e.g., suicidal ideation, psychotic symptoms, or dementia, that prevents informed consent.
* Using their opioids for cancer pain

Where this trial is running

Strängnäs, Sörmland and 2 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Chronic PainChronic Pain ManagementPrimary Care
Last reviewed 2026-06-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.