Improving pain control after laparoscopic colorectal surgery
Optimizing Postoperative Pain Control After Laparoscopic Colorectal Surgery by Supplementing Ultrasound-guided Erector Spinae Plane Block With Ketamine or Transdermal Fentanyl Patch
This study is testing whether a new pain management technique using a specific nerve block along with either ketamine or a fentanyl patch can help patients recovering from laparoscopic colorectal surgery feel better with fewer side effects.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 120 (estimated) |
| Ages | 21 Years and up |
| Sex | All |
| Sponsor | Ain Shams University Academic / other |
| Locations | 1 site (Cairo) |
| Trial ID | NCT06007378 on ClinicalTrials.gov |
What this trial studies
This study investigates the effectiveness of the erector spinae plane block (ESPB) technique combined with either ketamine or a transdermal fentanyl patch for managing postoperative pain in patients undergoing laparoscopic colorectal surgery. The aim is to determine which combination provides superior pain relief while minimizing side effects. The study will include patients classified as ASA physical status I or II, ensuring a focus on those with lower surgical risk. The interventions will compare the outcomes of different analgesic approaches to optimize postoperative care.
Who should consider this trial
Good fit: Ideal candidates are patients scheduled for laparoscopic colorectal surgery who are classified as ASA physical status I or II.
Not a fit: Patients with known allergies to the study medications or those with significant comorbidities such as hepatic, renal, or cardiac dysfunction may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could significantly enhance postoperative pain management for patients undergoing colorectal surgery.
How similar studies have performed: Previous studies have shown promising results with similar regional anesthesia techniques, suggesting potential for success in this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients undergoing laparoscopic colorectal surgery. * American Society of Anesthesiologists (ASA) physical status I or II. Exclusion Criteria: * Known allergy to one of the study medications. * Skin infections at the site of the needle puncture. * Hepatic, renal or cardiac dysfunction. * Patients diagnosed with obstructive sleep apnoea
Where this trial is running
Cairo
- Ain-Shams University Hospitals — Cairo, Egypt (Recruiting)
Study contacts
- Study coordinator: Ibrahim Mamdouh Esmat
- Email: ibrahim_mamdouh@med.asu.edu.eg
- Phone: 01001241928
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.