Clinical trial Recruiting at 4 sites Interventional Ages 18 and up

Improving opioid treatment and HIV prevention in prisons

Official title: PRIDE III Prison Interventions and HIV Prevention Collaboration

Run by Yale University · NCT06962033 · Data updated 2026-11-12

This study is trying to find out what makes it hard to provide opioid treatment in prisons in Tajikistan, Kyrgyzstan, Moldova, and Georgia, so that they can improve care for people with addiction and help prevent HIV.

Quick facts

Study typeInterventional
Ages18 Years and up
SexAll
Enrollment300 (estimated)
SponsorYale University
Academic / other
Locations5 sites (New Haven, Connecticut and 4 other locations)
StatusRecruiting
StartedNovember 5, 2024
Main results expectedDecember 2028
Study endsDecember 2028
Registry record updatedSeptember 10, 2026
Trial IDNCT06962033 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates include probation officers and individuals currently on probation who have a history of opioid injection.

Probably not a fit

Patients not currently involved in the justice system or those without a history of opioid use may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This project aims to identify barriers to the implementation of Opioid Agonist Therapy (OAT) within the justice systems of Tajikistan, Kyrgyzstan, Moldova, and Georgia. It involves creating NIATx learning collaboratives with prison OAT providers and probation officers to enhance the scale-up of OAT. Data will be collected from national OAT databases and through surveys administered to prison narcologists and probation officers every six months. Additionally, ethnographic methods will be employed to observe and interview probation clients and staff.

Why it matters

Potential benefit: If successful, this initiative could significantly improve access to opioid treatment and reduce HIV transmission among incarcerated populations.

How similar studies have gone: Previous studies have shown promise in implementing OAT in similar settings, indicating potential for success in this approach.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

Aim 1:

1. Quantitative surveys for prison OAT providers

   * Being 18 years or older
   * Being currently assigned and working as a probation OAT provider for a probation site
2. ECHO procedures

Aim 2:

1. Quantitative surveys for people in probation

   * Being 18 years or older
   * Screen yes to opioid injection on the online screener questionnaire
   * Currently in probation
2. Quantitative surveys for probation and prison officers

   * Being 18 years or older
   * Being currently assigned and working as a probation or prison officer at a probation site
3. Focus Groups (People in probation)

   * Being 18 years or older
   * Screen yes to opioid injection criteria on the online screener
   * Currently in probation
4. Focus Groups (Probation and prison officers)

   * Being 18 years or older
   * Being currently assigned and working as a probation or prison officer at a probation
   * Has more than 3 months of field experience
   * Works at a probation site within 25 kilometers of an OAT site

Exclusion Criteria:

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Where it's running

  • Alternative Georgia
    Tbilisi, Georgia
    Recruiting
  • AIDS Foundation East-West (AFEW)
    Bishkek, Kyrgyzstan
    Recruiting
  • Ngo Afi
    Chisinau, Moldova
    Recruiting
  • Institute for International Health and Education (IIHE)
    Dushanbe, Tajikistan
    Recruiting
  • Yale University
    New Haven, Connecticut, United States
    Not yet recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.