Improving naming treatment for people with aphasia after stroke
Integrating Complementary Learning Principles in Aphasia Rehabilitation Via Adaptive Modeling (Sub-study 1: Balancing Effortful and Errorless Learning Via Adaptive Naming Deadlines)
This study tests new ways to help people with aphasia after a stroke improve their naming skills and use them in daily life.
Quick facts
| Phase | Phase 2 |
|---|---|
| Study type | Interventional |
| Enrollment | 30 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | University of Pittsburgh Academic / other |
| Locations | 1 site (Pittsburgh, Pennsylvania) |
| Trial ID | NCT05653440 on ClinicalTrials.gov |
What this trial studies
This study evaluates new treatment approaches for individuals with aphasia, focusing on improving long-term retention and everyday use of naming abilities. It involves a randomized within-subjects crossover design with 30 participants who will undergo 8 treatment sessions across three different conditions. The conditions include accuracy-maximized, effort-maximized, and effort-accuracy balanced approaches, with assessments conducted at various intervals to measure progress. The study aims to enhance the effectiveness of picture-based naming treatments by balancing effortful and errorless learning.
Who should consider this trial
Good fit: Ideal candidates are individuals diagnosed with chronic aphasia due to a left hemisphere stroke, at least six months post-onset.
Not a fit: Patients with right hemisphere strokes or significant language comprehension impairments may not benefit from this study.
Why it matters
Potential benefit: If successful, this treatment could significantly improve the ability of patients with aphasia to recall and use words in daily life.
How similar studies have performed: While there have been studies on naming treatments for aphasia, this specific approach of balancing effort and errorless learning is novel and has not been extensively tested.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Existing diagnosis of chronic (\>6 months) aphasia subsequent to left hemisphere ischemic or hemorrhagic stroke. * Impaired performance on 2/8 sections of the Comprehensive Aphasia Test. Exclusion Criteria: * History of other acquired or progressive neurological disease. * Significant language comprehension impairments * Unmanaged drug / alcohol dependence. * Severe diagnosed mood or behavioral disorders that require specialize mental health interventions.
Where this trial is running
Pittsburgh, Pennsylvania
- Language Rehab and Cognition Lab, Department of Communication Sciences and Disorders, School of Health and Rehabilitation Sciences, University of Pittsburgh — Pittsburgh, Pennsylvania, United States (Recruiting)
Study contacts
- Principal investigator: William Evans, PhD — University of Pittsburgh
- Study coordinator: Alyssa Kelly, M.A., CCC-SLP
- Email: ank155@pitt.edu
- Phone: 412-648-3274
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.