Clinical trial Recruiting at 1 site Interventional Ages 18 to 65

Improving metabolism with neuromuscular electrical stimulation

Official title: Neuromuscular Electrical Stimulation: A Novel Treatment for Improving Metabolism

Run by University of Texas, El Paso · NCT06722391 · Data updated 2026-11-12

This study is testing if neuromuscular electrical stimulation can help overweight and obese people improve their insulin resistance and metabolism.

Quick facts

Study typeInterventional
Ages18 Years to 65 Years
SexAll
Enrollment80 (estimated)
SponsorUniversity of Texas, El Paso
Academic / other
Locations1 site (El Paso, Texas)
StatusRecruiting
StartedAugust 19, 2024
Main results expectedSeptember 1, 2029
Study endsSeptember 1, 2031
Registry record updatedOctober 20, 2026
Trial IDNCT06722391 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are overweight or obese individuals with a sedentary lifestyle and limited structured exercise.

Probably not a fit

Patients who are on medications affecting insulin sensitivity or those with substance abuse issues may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the effects of neuromuscular electrical stimulation (NMES) on improving insulin resistance in overweight and obese individuals. Participants will wear an accelerometer to track physical activity and follow a standardized diet before undergoing an 8-week intervention. They will be randomly assigned to one of four groups: a control group receiving sensory-level stimulation, an NMES group with higher intensity stimulation, a resistance training combined with NMES group, or a resistance training only group. The study aims to assess changes in insulin sensitivity before and after the intervention.

Why it matters

Potential benefit: If successful, this approach could significantly improve metabolic health and insulin sensitivity in overweight and obese patients.

How similar studies have gone: While the use of NMES for metabolic improvement is a novel approach, similar studies have shown promise in enhancing muscle function and metabolic outcomes.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Overweight/Obese (BMI ≥25)
* Sedentary Lifestyle: Physical Activity Level\<1.4
* Less than 150min/week of structured Exercise

Exclusion Criteria:

* Use of anti-hypertensive, lipid-lowering or insulin sensitizing medications
* Excessive alcohol, drug abuse, smoking
* Pregnant Women
* Unwilling to adhere to the study Intervention

Where it's running

  • University of Texas at El Paso
    El Paso, Texas, United States
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.