Improving mental fatigue in patients with Graves' disease
A Mental Fatigue Course to Graves' Disease Patients With Mental Fatigue -a Randomized Controlled Study
This study is testing if a special course to help with mental fatigue can improve symptoms and quality of life for people with Graves' disease.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 96 (estimated) |
| Ages | 18 Years to 72 Years |
| Sex | All |
| Sponsor | Vastra Gotaland Region Government |
| Locations | 1 site (Gothenburg) |
| Trial ID | NCT06134219 on ClinicalTrials.gov |
What this trial studies
This study aims to evaluate the effectiveness of a mental fatigue (MF) course in improving mental fatigue symptoms in patients diagnosed with Graves' disease. Participants will receive either the MF course in addition to standard care or standard care alone. The study will measure changes in mental fatigue, mental capacity, quality of life, and overall function. The goal is to determine if the MF course can provide significant benefits to those experiencing persistent mental fatigue related to their condition.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18-72 who have been diagnosed with Graves' disease and experience significant mental fatigue.
Not a fit: Patients with other diseases associated with mental fatigue or those who are pregnant or lactating may not benefit from this study.
Why it matters
Potential benefit: If successful, this intervention could significantly enhance the quality of life and cognitive function for patients suffering from mental fatigue due to Graves' disease.
How similar studies have performed: While there is limited research specifically on MF courses for Graves' disease, studies addressing mental fatigue in other chronic conditions have shown promising results.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * 18-72 years old * 15-72 months since first Graves' diagnosis * high free thyroxin and thyroid antibodies (TRAb) at diagnosis * euthyroid the last 6 months normal thyroid hormone levels at inclusion * symptoms on MF in connection to Graves diagnosis * MF-scale ≥10.5 points Exclusion criteria: * other diseases or situations that may be associated with mental fatigue (such as other active inflammatory disease, neurological disease) * pregnancy * lactation * assessment that the patient cannot follow the study protocol.
Where this trial is running
Gothenburg
- Agneta Lindo — Gothenburg, Sweden (Recruiting)
Study contacts
- Principal investigator: Helena Filipsson Nyström — Sahlgrenska Universitet sjukhus
- Study coordinator: Agneta Lindo
- Email: agneta.lindo@vgregion.se
- Phone: +4676-6185481
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.