Clinical trial Recruiting at 2 sites Interventional Ages 11 and up

Improving memory and decision-making in at-risk youth

Official title: Train Your Brain 2.0: Improving Memory and Decision Making to Improve Outcomes Among Youth - A Randomized Controlled Trial

Run by Wayne State University · NCT06242704 · Data updated 2026-11-12

This study is testing a computer-based memory training program to see if it can help young people aged 11 to 15 in underserved areas make better decisions and reduce their risk of substance misuse.

Quick facts

Study typeInterventional
Ages11 Years and up
SexAll
Enrollment72 (estimated)
SponsorWayne State University
Academic / other
Locations2 sites (Flint, Michigan and 1 other locations)
StatusRecruiting
StartedJune 25, 2024
Main results expectedAugust 1, 2026
Study endsAugust 1, 2026
Registry record updatedMay 25, 2025
Trial IDNCT06242704 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are adolescents aged 11 to 15 who have experienced early childhood adversity and are willing to participate in computer-based training.

Probably not a fit

Patients currently experiencing psychological disturbances or substance use disorders may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial aims to deliver a computer-based working memory training program to enhance delay discounting and prevent substance misuse among adolescents aged 11 to 15 in underserved areas. The study will assess changes in delay discounting as a mechanism for reducing substance use during early adolescence, particularly among those exposed to adverse childhood experiences. Participants will engage in computer-based training over 5-8 weeks, with follow-up evaluations to determine the effectiveness of the intervention in improving cognitive skills and reducing substance use risk.

Why it matters

Potential benefit: If successful, this intervention could significantly reduce the risk of substance misuse among at-risk adolescents by improving their decision-making and memory skills.

How similar studies have gone: Previous studies have shown promise in using computer-based interventions to improve cognitive skills and reduce substance use risk, making this approach both relevant and potentially impactful.

Who can join: the full rules

Show full inclusion / exclusion criteria
Adolescent Inclusion Criteria:

1. Between the ages of 11 and 15 and have a parent/guardian willing to provide consent for their participation
2. Proficient in English
3. Willing to commit to participate in computer-based trainings over the course of 5-8 weeks (duration dependent on site)
4. Access to internet services, cell phone, and/or email
5. Willing to receive/send study-related text messages

Adolescent Exclusion Criteria:

1. Self-disclosure or identification with psychological disturbance, suicidality, or evidence of active suicide ideation
2. Self-disclosure of current substance use disorder

Parent Inclusion Criteria:

1. Provide consent for child's participation in study
2. Proficient in English
3. Access to internet services, cell phone, and/or email
4. Willing to receive/send study-related text messages

Parent Exclusion Criteria:

1. Self-disclosure or identification with psychosis, suicidality, or evidence of active suicide ideation
2. Self-disclosure of current substance use disorder

Where it's running

  • Freedom Schools Collaborative
    Flint, Michigan, United States
    Recruiting
  • Ernest T. Ford Recreation Center
    Highland Park, Michigan, United States
    Recruiting

Study contacts

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.