Improving memory and decision-making in at-risk youth

Train Your Brain 2.0: Improving Memory and Decision Making to Improve Outcomes Among Youth - A Randomized Controlled Trial

NA · Wayne State University · NCT06242704

This study is testing a computer-based memory training program to see if it can help young people aged 11 to 15 in underserved areas make better decisions and reduce their risk of substance misuse.

Quick facts

PhaseNA
Study typeInterventional
Enrollment72 (estimated)
Ages11 Years and up
SexAll
SponsorWayne State University (other)
Locations2 sites (Flint, Michigan and 1 other locations)
Trial IDNCT06242704 on ClinicalTrials.gov

What this trial studies

This clinical trial aims to deliver a computer-based working memory training program to enhance delay discounting and prevent substance misuse among adolescents aged 11 to 15 in underserved areas. The study will assess changes in delay discounting as a mechanism for reducing substance use during early adolescence, particularly among those exposed to adverse childhood experiences. Participants will engage in computer-based training over 5-8 weeks, with follow-up evaluations to determine the effectiveness of the intervention in improving cognitive skills and reducing substance use risk.

Who should consider this trial

Good fit: Ideal candidates for this study are adolescents aged 11 to 15 who have experienced early childhood adversity and are willing to participate in computer-based training.

Not a fit: Patients currently experiencing psychological disturbances or substance use disorders may not benefit from this study.

Why it matters

Potential benefit: If successful, this intervention could significantly reduce the risk of substance misuse among at-risk adolescents by improving their decision-making and memory skills.

How similar studies have performed: Previous studies have shown promise in using computer-based interventions to improve cognitive skills and reduce substance use risk, making this approach both relevant and potentially impactful.

Eligibility criteria

Show full inclusion / exclusion criteria
Adolescent Inclusion Criteria:

1. Between the ages of 11 and 15 and have a parent/guardian willing to provide consent for their participation
2. Proficient in English
3. Willing to commit to participate in computer-based trainings over the course of 5-8 weeks (duration dependent on site)
4. Access to internet services, cell phone, and/or email
5. Willing to receive/send study-related text messages

Adolescent Exclusion Criteria:

1. Self-disclosure or identification with psychological disturbance, suicidality, or evidence of active suicide ideation
2. Self-disclosure of current substance use disorder

Parent Inclusion Criteria:

1. Provide consent for child's participation in study
2. Proficient in English
3. Access to internet services, cell phone, and/or email
4. Willing to receive/send study-related text messages

Parent Exclusion Criteria:

1. Self-disclosure or identification with psychosis, suicidality, or evidence of active suicide ideation
2. Self-disclosure of current substance use disorder

Where this trial is running

Flint, Michigan and 1 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Behavior, Health, delay discounting, computer-based intervention, executive functioning, substance use, working memory

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.