Improving medication adherence for older adults with hypertension

Improving Hypertension Medication Adherence for Older Adults

Not applicable Interventional University of Arizona · NCT05610059

This study is testing a new system to help older adults with high blood pressure stick to their medication and manage their condition better.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment224 (estimated)
Ages65 Years and up
SexAll
SponsorUniversity of Arizona Academic / other
Locations2 sites (Tucson, Arizona and 1 other locations)
Trial IDNCT05610059 on ClinicalTrials.gov

What this trial studies

This randomized controlled trial aims to evaluate the effectiveness and scalability of a blood pressure technology system intervention for older adults with hypertension. A total of 224 participants aged 65 and older will be enrolled, with half receiving standard information about hypertension and medications, while the other half will also receive additional strategies for medication adherence and blood pressure management. Participants will be monitored over a 6-month period, with assessments at 3 and 6 months to measure outcomes related to medication adherence and blood pressure control.

Who should consider this trial

Good fit: Ideal candidates are older adults aged 65 and above who are currently taking at least one hypertension medication and have demonstrated low adherence to their medication regimen.

Not a fit: Patients who are experiencing severe depression, cognitive impairment, or have been advised by their healthcare provider to withhold their blood pressure medication may not benefit from this study.

Why it matters

Potential benefit: If successful, this intervention could significantly improve medication adherence and blood pressure management in older adults, leading to better health outcomes.

How similar studies have performed: Other studies have shown promise in improving medication adherence through technology-based interventions, suggesting that this approach may be effective.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* age 65 years or older
* self-manage at least one hypertension medication
* able to read and speak English
* willing to participate in the study for six months
* currently have and use an Apple iPhone
* have hypertension medication adherence ≤ 90% in the last 2 weeks of the 4-week baseline monitoring period using an AARDEX MEMS® cap

Exclusion Criteria:

* have inadequate visual acuity (worse than 20/50 corrected near vision on Snellen test)
* experience severe depression (\> 11 on Geriatric Depression Scale Short Form, GDS-15)
* are at risk for cognitive impairment (\< 23 on Montreal Cognitive Assessment, MoCA)
* been instructed by their healthcare provider to withhold their blood pressure medication

Where this trial is running

Tucson, Arizona and 1 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions AgingMedication AdherenceHypertension
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.