Improving measures of nutrition, inflammation, kidney function, body composition, and hydration in older adults
Official title: Methods for Assessing Nutrition, Inflammation, Kidney Function, Aging, Body Composition, and Hydration Among Older Patients - An Observational Study (MIKADO)
Run by Hvidovre University Hospital · NCT07501195 · Data updated 2026-11-12
This project will test whether modern blood tests and body-measure techniques give more accurate estimates of nutrition and kidney health for hospitalized people aged 65 and older.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 65 Years and up |
| Sex | All |
| Enrollment | 500 (estimated) |
| Sponsor | Hvidovre University Hospital Academic / other |
| Locations | 1 site (Copenhagen) |
| Status | Recruiting |
| Started | March 1, 2026 |
| Main results expected | March 2028 |
| Study ends | September 2035 |
| Registry record updated | March 30, 2026 |
| Trial ID | NCT07501195 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Hospitalized adults aged 65 and older who can read and speak Danish and cooperate, including specific subgroups such as acutely admitted patients, people aged 90+, individuals with BMI ≥35, long-term high-dose prednisolone users, and non-traumatic lower-limb amputees.
✕Probably not a fit
Patients in isolation, receiving terminal care, actively suicidal, on immune-suppressing treatment, with oedema, currently undergoing cancer treatment, or unable to read/speak Danish or cooperate cognitively are excluded and unlikely to benefit from participation.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational project compares modern biomarkers, body-composition measures, and hydration assessments with current clinical and laboratory gold standards to improve diagnosis of malnutrition and kidney disease in older hospitalized patients. Participants are recruited at Hvidovre Hospital across several groups, including acutely admitted patients, people aged 90+, those with BMI ≥35, long-term high-dose prednisolone users, and non-traumatic lower-limb amputees. The study collects blood-based biomarkers, inflammation markers, body composition and hydration measurements and compares them to established reference methods. It also analyzes how age, inflammation, body composition and hydration affect diagnostic accuracy.
Why it matters
Potential benefit: If successful, this work could lead to more accurate and earlier identification of malnutrition and kidney problems, enabling better-targeted care for older patients.
How similar studies have gone: Previous research has shown individual biomarkers and body-composition methods can improve diagnostic accuracy, but applying and comparing multiple modern modalities together in older hospitalized populations is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * 65 years or older (group 1, 4 and 5) * 90 years or older (group 3) * Acute admission (group 1, 2) * Cognitively able to cooperate (group 1) * Able to read and speak Danish (group 1, 2, 3, 4, 5, 6) * BMI ≥ 35 kg/m2 (group 4) * Prednisolon treatment for COPD (≥ 37,5 mg daily) (group 5) * Amputation(s) of crus or femur (non-traumatic) (group 6) Exclusion Criteria: * Isolation (group 1, 2, 3, 4, 5, 6) * Terminal treatment (group 1, 2, 3, 4, 5, 6) * Suicidal (group 1, 2, 3, 4, 5, 6) * Active Immune suppressing treatment (group 2, 3, 4, 5, 6) * Oedemas (group 2, 3, 4, 5, 6) * In active treatment for cancer (group 2, 3, 4, 5, 6)
Where it's running
-
Hvidovre Hospital
Copenhagen, Denmark Recruiting
Study contacts
- Principal investigator: Ove Andersen, Professor — Department of clinical research, Copenhagen University Hospital
- Study coordinator: Ove OA Andersen, Professor
- Email: ove.andersen@regionh.dk
- Phone: 004538626719
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.