Improving management of eosinophilic esophagitis in children and adolescents

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This project focuses on enhancing the care for children and adolescents diagnosed with eosinophilic esophagitis (EoE) through a collaborative effort between pediatric units at Oslo University Hospital and Helse Bergen in Norway. The study aims to systematically explore existing and new non-invasive biomarkers to reduce the need for invasive procedures like endoscopies and complex elimination diets. By identifying predictive biomarkers at diagnosis and follow-up, the study seeks to improve treatment outcomes and patient quality of life.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* a diagnosis of eosinophilic esophagitis
* suspected but not yet confirmed eosinophilic esophagitis

Exclusion Criteria:

* chronic severe conditions that preclude general anaestesia
* lack of consent

Where it's running

• Haukeland University Hospital
  Bergen, Norway Recruiting
• OsloUH
  Oslo, Norway Recruiting

Study contacts

• Principal investigator: Ketil Størdal, PhD — University of Oslo
• Study coordinator: Ketil Størdal, PhD
• Email: ketil.stordal@medisin.uio.no
• Phone: +4748272337

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Upadacitinib for Eosinophilic Esophagitis in adults not responding to standard therapy

  This study tests whether upadacitinib, taken with topical corticosteroids, can reduce disease activity in adults with eosinophilic esophagitis who still have symptoms.

  Recruiting Phase 2 University of North Carolina, Chapel Hill · Chapel Hill, North Carolina and 1 other locations · NCT07588568

• A registry for adults with esophageal movement and reflux problems.

  This project will collect esophageal function tests (manometry, pH-impedance, FLIP) and clinical data from adults with reflux or swallowing symptoms to see if combining these results helps guide diagnosis and long-term care.

  Recruiting IRCCS San Raffaele · Milan, Lombardy · NCT07506746

• Using a mucosal impedance device to help diagnose chronic esophageal problems

  This test tries a mucosal impedance device during upper endoscopy to see if it helps diagnose people with chronic reflux (GERD) or eosinophilic esophagitis.

  Recruiting Medical College of Wisconsin · Milwaukee, Wisconsin · NCT07227506

• Esophageal string test to screen for eosinophilic esophagitis in adults of African descent with swallowing problems

  This study will test whether a 1-hour esophageal string test can detect eosinophilic esophagitis in adults born in Africa (or with African parents) who have trouble swallowing.

  Recruiting National Institutes of Health Clinical Center (CC) · Bethesda, Maryland and 2 other locations · NCT07027826

• How common FIRE is and what it looks like in children with eosinophilic esophagitis

  This project will see how often and in what ways Food Induced Immediate Response of the Esophagus (FIRE) occurs in children aged 6–17 who have eosinophilic esophagitis.

  Recruiting University Hospital, Angers · Angers and 1 other locations · NCT06972147

• Comparing dupilumab and topical corticosteroids for treating eosinophilic esophagitis

  This study is testing whether a new weekly injection called dupilumab works better than a daily swallowed medication for treating eosinophilic esophagitis in young people aged 12 to 25.

  Recruiting Phase 2 University of Colorado, Denver · Aurora, Colorado · NCT06705387

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.