Improving lung function in sickle cell disease with acupuncture-like stimulation
Official title: Pulmonary Functions in Sickle Cell Disease: Response of Adding Acu-TENS to Inspiratory Muscle Training
Run by Cairo University · NCT06757829 · Data updated 2026-11-12
This study is testing whether combining breathing exercises with a special type of electrical stimulation can help improve lung function in people with sickle cell disease.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 20 Years to 50 Years |
| Sex | All |
| Enrollment | 40 (estimated) |
| Sponsor | Cairo University Academic / other |
| Locations | 1 site (Dokki, Giza Governorate) |
| Status | Recruiting |
| Started | December 15, 2024 |
| Main results expected | May 1, 2025 |
| Study ends | May 1, 2025 |
| Registry record updated | January 3, 2025 |
| Trial ID | NCT06757829 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are non-obese patients diagnosed with sickle cell disease.
✕Probably not a fit
Patients with systemic, chest, renal, hepatic, or neurological diseases, as well as those experiencing vaso-occlusive crises, may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study investigates the effects of inspiratory muscle training (IMT) combined with acupuncture-like transcutaneous electrical nerve stimulation (AC-tens) on pulmonary function in patients with sickle cell disease. Forty participants will be divided into two groups: one receiving IMT and AC-tens, and the other receiving only IMT. Each group will undergo three sessions per week for 12 weeks, with specific training protocols designed to enhance respiratory function. The study aims to assess the efficacy of these interventions in alleviating pulmonary complications associated with sickle cell disease.
Why it matters
Potential benefit: If successful, this approach could significantly improve respiratory function and quality of life for patients with sickle cell disease.
How similar studies have gone: While the combination of IMT and AC-tens is a novel approach, similar studies have shown positive outcomes with respiratory training in patients with pulmonary complications.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * sickle cell disease patients * non obese patients Exclusion Criteria: * patients with any systemic or chest or renal or hepatic or neurological diseases * women with lactation or pregnancy * patients atacks of vasoocclusive crisis
Where it's running
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faculty of physical therapy Cairo university
Dokki, Giza Governorate, Egypt Recruiting
Study contacts
- Principal investigator: Ali Ismail, lecturer — Cairo University
- Study coordinator: Ali Isamil, Lecturer
- Email: ali.mohamed@pt.cu.edu.eg
- Phone: 0201005154209
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.