Improving knee surgery with robotic systems

Optimization of Total Knee Arthroplasty Using Robotic Systems

NA · I.M. Sechenov First Moscow State Medical University · NCT05712291

This study is testing if using advanced robotic systems during knee surgery can help people with knee osteoarthritis recover better and have more accurate results compared to traditional methods.

Quick facts

PhaseNA
Study typeInterventional
Enrollment250 (estimated)
Ages21 Years to 90 Years
SexAll
SponsorI.M. Sechenov First Moscow State Medical University (other)
Locations1 site (Moscow)
Trial IDNCT05712291 on ClinicalTrials.gov

What this trial studies

This study aims to optimize total knee arthroplasty (TKA) using advanced robotic systems to enhance surgical outcomes for patients with knee osteoarthritis. It will develop algorithms for preoperative planning and surgical intervention, focusing on patients with varying degrees of bone density and osteophytes. The study will include both retrospective and prospective observations of 250 patients, assessing the effectiveness of robotic-assisted techniques compared to traditional methods. By leveraging robotic technology, the study seeks to reduce variability in surgical procedures and improve the accuracy of prosthesis alignment.

Who should consider this trial

Good fit: Ideal candidates are adults aged 21 to 90 with stage 3-4 knee osteoarthritis and significant pain.

Not a fit: Patients with severe comorbidities or those unwilling to undergo surgical treatment may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could lead to improved surgical outcomes and quality of life for patients undergoing knee arthroplasty.

How similar studies have performed: Other studies have shown promising results with robotic-assisted surgeries, indicating potential for success in this novel application.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Availability of written informed consent of the patient to participate in the study;
2. Patients with stage 3-4 osteoarthritis of the knee joint (according to Kellgren-Lawrence).
3. Men and women from 21 to 90 years old.
4. Pain in the knee joint above 3 points according to VAS
5. Opportunity for observations during the entire study period (12 months);
6. Mental adequacy, ability, willingness to cooperate and to fulfill the doctor's recommendations.

Exclusion Criteria:

1. Refusal of the patient from surgical treatment;
2. Presence of contraindications to surgical treatment;
3. Severe forms of diabetes mellitus (glycosylated hemoglobin\> 9%);
4. Diseases of the blood (thrombopenia, thrombocytopenia, anemia with Hb \<90 g / l);
5. The patient's unwillingness to conscious cooperation.
6. Refusal of the patient to participate in the study;
7. Non-compliance with the hospital regimen, according to the order of the Ministry of Health and Social Development of Russia dated 01.08.07, No. 514;
8. The impossibility of observing the patient within the control period after the operation.

Where this trial is running

Moscow

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Knee Osteoarthritis, total knee arthroplasty, robotic total knee arthroplasty, the active robotic surgical system, robotic system in orthopedic

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.