Improving jaw reconstruction for oral cancer patients using virtual planning

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial evaluates the effectiveness of Virtual Surgical Planning (VSP) compared to traditional Free-Hand Surgery (FHS) for patients undergoing mandibular reconstruction due to oral cavity cancer. Participants will be randomly assigned to receive either VSP or FHS, and their outcomes will be assessed through postoperative CT scans at 12 months to compare bony union rates. Additionally, the study will analyze other complications, reconstruction accuracy, quality of life, and functional outcomes, along with an economic evaluation of VSP. The goal is to determine if VSP can improve surgical results and patient experiences.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* primary diagnosis requiring mandibulectomy and fibular or scapular free flap reconstructive surgery
* are over the age of 18
* cognitive ability and language skills that allow participation in the trial
* provide informed consent

Exclusion Criteria:

* severe comorbidities including metastatic disease
* do not have a recent (within 30 days) CT scan and are unable/unwilling to receive a head CT scan at the latest 6 days prior to surgery
* prior history of head or neck cancer within last 5 years
* prior history of head or neck radiation treatment at any time
* pregnant of lactating women

Where it's running

• Vancouver General Hospital
  Vancouver, British Columbia, Canada Recruiting

Study contacts

• Study coordinator: Eitan Prisman, MD, FRCSC
• Email: eitan.prisman@ubc.ca
• Phone: 6048754126

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.