Improving HPV vaccination rates through provider recommendations
Official title: Effectiveness and Mechanisms of Multilevel Implementation Strategies to Improve Provider Recommendation and Advance HPV Vaccination: a Cluster Randomized Trial
Run by Kaiser Permanente · NCT05365048 · Data updated 2026-11-12
This study is testing if getting healthcare providers to recommend the HPV vaccine can help more teens get vaccinated.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 21 Years to 70 Years |
| Sex | All |
| Enrollment | 301201 (estimated) |
| Sponsor | Kaiser Permanente Academic / other |
| Locations | 1 site (Pasadena, California) |
| Status | Recruiting |
| Started | March 21, 2022 |
| Main results expected | December 31, 2025 |
| Study ends | June 30, 2026 |
| Registry record updated | May 20, 2025 |
| Trial ID | NCT05365048 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are parents of HPV vaccine-eligible children aged 9-12 years who visit participating pediatric clinics.
✕Probably not a fit
Patients who may not benefit from this study include those with children older than 12 years or those who do not have a clinic visit during the study period.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study aims to enhance HPV vaccination rates among US teens by implementing a local tailoring strategy that focuses on provider recommendations. It addresses the barriers to vaccination by involving healthcare providers, including physicians, nurses, and medical assistants, in pediatric clinics. The intervention seeks to understand and improve the effectiveness of provider recommendations, which are crucial for increasing vaccine uptake. By analyzing multilevel factors influencing vaccination, the study aims to create a more comprehensive approach to overcoming existing barriers.
Why it matters
Potential benefit: If successful, this study could significantly increase HPV vaccination rates, thereby reducing the incidence of HPV-related cancers among adolescents.
How similar studies have gone: Previous studies have shown that strong provider recommendations can improve vaccination rates, but this approach aims to address the multifaceted barriers in a novel way.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * All KPSC pediatric clinics. * All providers (physicians, nurses, and medical assistants) and department administrators from the pediatric department. * Parents of HPV vaccine-eligible children (9-12 years old). Exclusion Criteria: * Providers and administrators who do not work for the pediatric department * Parents of children older than 12 years and/or who did not have a clinic visit in the study period.
Where it's running
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Kaiser Permanente Southern California
Pasadena, California, United States Recruiting
Study contacts
- Principal investigator: Erin Hahn, PhD — KPSC Department of Research and Evaluation
- Study coordinator: Nancy Takahashi Cannnizzaro, PhD
- Email: Nancy.Takahashi@kp.org
- Phone: 626-564-7663
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.