Improving HIV medication adherence using a smartphone app and health coaching

mHealth Facilitated Intervention to Improve Medication Adherence Among Persons Living With HIV

Not applicable Interventional Rhode Island Hospital · NCT05046392

This study is testing whether a smartphone app and health coaching can help people with HIV remember to take their medication better than just health coaching alone.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment400 (estimated)
Ages18 Years and up
SexAll
SponsorRhode Island Hospital Academic / other
Locations2 sites (Atlanta, Georgia and 1 other locations)
Trial IDNCT05046392 on ClinicalTrials.gov

What this trial studies

This study tests an innovative intervention aimed at improving medication adherence among individuals living with HIV. Participants will receive a health coaching session along with access to a smartphone application that provides medication reminders and allows for remote communication with their health coach. The study will enroll 400 participants across two sites, with a focus on comparing the effectiveness of the app-enhanced intervention against a standard health coaching session. Data will be collected through interviews at multiple time points to assess adherence to antiretroviral therapy (ART) and other related factors.

Who should consider this trial

Good fit: Ideal candidates for this study are adults aged 18 and older who are diagnosed with HIV, prescribed ART, and have a detectable viral load with less than 100% self-reported medication adherence.

Not a fit: Patients with cognitive impairments, active psychosis, or those who are not fluent in English may not benefit from this study.

Why it matters

Potential benefit: If successful, this intervention could significantly enhance medication adherence among people living with HIV, leading to better health outcomes and reduced transmission rates.

How similar studies have performed: Previous studies have shown promise in using mobile health interventions to improve medication adherence, indicating that this approach has potential for success.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* at least 18 years of age
* prescribed ART
* diagnosed with HIV
* detectable viral load (\>20 copies/mL) in past 6 months
* less than 100% self-reported medication adherence

Exclusion Criteria:

* physical impairments that would prevent completion of the intervention
* cognitive impairments that jeopardize informed consent and/or intervention comprehension
* active psychosis
* not fluent in English

Where this trial is running

Atlanta, Georgia and 1 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions HIVMedication AdherenceTelemedicinemHealthHealth Coaching
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.